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Editorial
. 2022 Sep;11(9):3006-3011.
doi: 10.21037/tcr-22-1984.

Double trouble: combined large-cell neuroendocrine and small-cell lung carcinoma

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Editorial

Double trouble: combined large-cell neuroendocrine and small-cell lung carcinoma

David Fisch et al. Transl Cancer Res. 2022 Sep.
No abstract available

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-22-1984/coif). PC declares research funding from AstraZeneca, Amgen, Merck, Novartis, Roche, and Takeda; speaker’s honoraria from AstraZeneca, Novartis, Pfizer, Roche, Takeda; support for attending meetings from AstraZeneca, Daiichi Sankyo, Eli Lilly, Gilead, Janssen, Novartis, Takeda; and personal fees for participating to advisory boards from Boehringer Ingelheim, Chugai, Pfizer and Roche; all outside the submitted work. The other author has no conflicts of interest to declare.

Comment on

References

    1. Volckmar AL, Leichsenring J, Kirchner M, et al. Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases. Int J Cancer 2019;145:649-61. 10.1002/ijc.32133 - DOI - PubMed
    1. Reck M, Rodríguez-Abreu D, Robinson AG, et al. Five-Year Outcomes With Pembrolizumab Versus Chemotherapy for Metastatic Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score ≥ 50. J Clin Oncol 2021;39:2339-49. 10.1200/JCO.21.00174 - DOI - PMC - PubMed
    1. Ai L, Li J, Ye T, et al. Progressive neuroendocrine tumor of lung with combined categories in metastatic site: a case report. Transl Cancer Res 2022;11:2438-42. 10.21037/tcr-21-2793 - DOI - PMC - PubMed
    1. Fisch D, Bozorgmehr F, Kazdal D, et al. Comprehensive Dissection of Treatment Patterns and Outcome for Patients With Metastatic Large-Cell Neuroendocrine Lung Carcinoma. Front Oncol 2021;11:673901. 10.3389/fonc.2021.673901 - DOI - PMC - PubMed
    1. Dumoulin DW, Dingemans AC, Aerts JGJV, et al. Immunotherapy in small cell lung cancer: one step at a time: a narrative review. Transl Lung Cancer Res 2021;10:2970-87. 10.21037/tlcr-20-630 - DOI - PMC - PubMed