Lower risk of Multi-system inflammatory syndrome in children (MIS-C) with the omicron variant

Laura Lopez¹, David Burgner², Catherine Glover¹, Jeremy Carr³, Julia Clark⁴, Alison Boast², Nan Vasilunas⁵, Brendan McMullan⁶, Joshua R Francis⁷, Asha C Bowen⁸, Christopher C Blyth⁸, Kristine Macartney^{1

9}, Nigel W Crawford², Emma Carey¹, Nicholas Wood^{1

9}, Philip N Britton⁹; Australian Vasculitis Working Group and Paediatric Active Enhanced Disease Surveillance (PAEDS) network

Affiliations

¹ National Centre for Immunisation Research and Surveillance, Westmead, New South Wales, Australia.
² Royal Children's Hospital, Melbourne and Murdoch Children's Research Institute, Victoria, Australia.
³ Monash Children's Hospital, Melbourne, Victoria, Australia.
⁴ Queensland Children's Hospital, Brisbane, Queensland, Australia.
⁵ Women's and Children's Hospital, Adelaide, South Australia, Australia.
⁶ Sydney Children's Hospital, Randwick, New South Wales, Australia.
⁷ Royal Darwin Hospital, Darwin, Northern Territory, Australia.
⁸ Perth Children's Hospital, Perth, Western Australia, Australia.
⁹ The Children's Hospital at Westmead and University of Sydney, New South Wales, Australia.

PMID: 36237982
PMCID: PMC9541565
DOI: 10.1016/j.lanwpc.2022.100604

Lower risk of Multi-system inflammatory syndrome in children (MIS-C) with the omicron variant

Laura Lopez et al. Lancet Reg Health West Pac. 2022.

. 2022 Oct 7:27:100604.

doi: 10.1016/j.lanwpc.2022.100604. eCollection 2022 Oct.

Authors

Affiliations

¹ National Centre for Immunisation Research and Surveillance, Westmead, New South Wales, Australia.
² Royal Children's Hospital, Melbourne and Murdoch Children's Research Institute, Victoria, Australia.
³ Monash Children's Hospital, Melbourne, Victoria, Australia.
⁴ Queensland Children's Hospital, Brisbane, Queensland, Australia.
⁵ Women's and Children's Hospital, Adelaide, South Australia, Australia.
⁶ Sydney Children's Hospital, Randwick, New South Wales, Australia.
⁷ Royal Darwin Hospital, Darwin, Northern Territory, Australia.
⁸ Perth Children's Hospital, Perth, Western Australia, Australia.
⁹ The Children's Hospital at Westmead and University of Sydney, New South Wales, Australia.

PMID: 36237982
PMCID: PMC9541565
DOI: 10.1016/j.lanwpc.2022.100604

Erratum in

Corrigendum to "Lower risk of multi-system Inflammatory Syndrome in Children (MIS-C) with the Omicron variant" [The Lancet Regional Health - Western Pacific 27 (2022) 100604].
Lopez L, Burgner D, Glover C, Carr J, Clark J, Boast A, Vasilunas N, McMullan B, Francis JR, Bowen AC, Blyth CC, Macartney K, Crawford NW, Carey E, Wood N, Britton PN; Australian Vasculitis Working Group; Paediatric Active Enhanced Disease Surveillance (PAEDS) network. Lopez L, et al. Lancet Reg Health West Pac. 2023 Jun;35:100808. doi: 10.1016/j.lanwpc.2023.100808. Epub 2023 May 30. Lancet Reg Health West Pac. 2023. PMID: 37274779 Free PMC article.

No abstract available

Keywords: MIS-C, Multi-system Inflammatory Syndrome in Children; PAEDS, Paediatric Active Enhanced Disease Surveillance network.

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Conflict of interest statement

Dr David Burgner reports an Investigator grant from the National Health and Medical Research Council and voluntary position at the Kawasaki Disease Foundation, Australia. Dr Asha C. Bowen reports an Investigator grant from the National Health and Medical Research Council and is Vice President of the World Society of Pediatric Infectious Diseases. The rest of the authors have no conflicts of interest relevant to this article to disclose.

References

1. Dionne A, Son MB, Randolph AG. An update on multisystem inflammatory syndrome in children related to SARS-CoV-2. Pediatr Infect Dis J. 2022;41(1):e6. - PMC - PubMed
1. Dinsmore N, McRae JE, Quinn HE, et al. Paediatric active enhanced disease surveillance (PAEDS) 2019: prospective hospital-based surveillance for serious paediatric conditions. Commun Dis Intell (2018) 2021;45 doi: 10.33321/cdi.2021.45.53. Epub 30/9/2021. - DOI - PubMed
1. Wurzel D, McMinn A, Hoq M, et al. Prospective characterisation of SARS-CoV-2 infections among children presenting to tertiary paediatric hospitals across Australia in 2020: a national cohort study. BMJ Open. 2021;11(11) - PMC - PubMed
1. COVID-19 National Incident Room Surveillance Team. COVID-19 Australia: Epidemiology Report updated 22 Feb 2022, Technical supplement [accessed 9 June 2022; cited 10 June 2022]. Available from: Department of Health | Coronavirus disease 2019 (COVID-19) epidemiology reports, Australia, 2020–2022
1. Cohen JM, Carter MJ, Cheung CR, Ladhani S, Evelina PIMS-TS Study Group Lower risk of multisystem inflammatory syndrome in children (MIS-C) with the delta and omicron variants of SARS-CoV-2. Clin Infect Dis. 2022 doi: 10.1093/cid/ciac553. - DOI - PMC - PubMed

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Lower risk of Multi-system inflammatory syndrome in children (MIS-C) with the omicron variant

Affiliations

Lower risk of Multi-system inflammatory syndrome in children (MIS-C) with the omicron variant

Authors

Affiliations

Erratum in

Conflict of interest statement

References

LinkOut - more resources

Full Text Sources