Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Oct 14;194(12):886.
doi: 10.1007/s10661-022-10558-y.

Trends and thresholds on bacterial degradation of bisphenol-A endocrine disruptor - a concise review

N Mahesh  1 , S Shyamalagowri  2 , T G Nithya  3 , J Aravind  4 , M Govarthanan  5 , M Kamaraj  6
Affiliations
Review

Trends and thresholds on bacterial degradation of bisphenol-A endocrine disruptor - a concise review

N Mahesh et al. Environ Monit Assess. .

Abstract

Bisphenol-A (BPA) is a monomer found in polycarbonate plastics, food cans, and other everyday chemicals; this monomer and its counterparts are widely used, culminating in its presence in water, soil, sediment, and the atmosphere. Furthermore, because of its estrogenic and genotoxic properties, it has been acknowledged as an endocrine disruptor; contamination of BPA in the environment is becoming a growing concern, and ways to effectively mitigate BPA from the environment are currently explored. Hence, the focal point of the review is to collate the bacterial degradation of BPA with the proposed degradation mechanism, explicitly focusing on researches published between 2017 and 2022. BPA breakdown is dependent primarily on bacterial metabolism, although numerous factors influence its fate in the environment. The metabolic routes for BPA breakdown in crucial bacterial strains were postulated, sourced on the transformed metabolite-intermediates perceived through degradation; enzymes and genes associated with the bacterial degradation of BPA have also been included in this review. This review will be momentous to generate a conceptual strategy and stimulate the progress on bacterial mitigation of BPA as a path to a sustainable cleaner environment.

Keywords: Bacteria; Bisphenol-A; Endocrine disruptor; Enzyme; Intermediates; Pathway.

PubMed Disclaimer

References

    1. Alexander, H. C., Dill, D. C., Smith, L. W., Guiney, P. D., & Dorn, P. (1988). Bisphenol a: Acute aquatic toxicity. Environmental Toxicology and Chemistry, 7(1), 19–26. https://doi.org/10.1002/ETC.5620070104 - DOI
    1. Babatabar, S., Zamir, S. M., Shojaosadati, S. A., Yakhchali, B., & Zarch, A. B. (2019). Cometabolic degradation of bisphenol A by pure culture of Ralstonia eutropha and metabolic pathway analysis. Journal of Bioscience and Bioengineering, 127(6), 732–737. https://doi.org/10.1016/J.JBIOSC.2018.12.001 - DOI
    1. Bilal, M., Rasheed, T., Iqbal, H. M. N., & Yan, Y. (2018). Peroxidases-assisted removal of environmentally-related hazardous pollutants with reference to the reaction mechanisms of industrial dyes. Science of the Total Environment, 644, 1–13. https://doi.org/10.1016/J.SCITOTENV.2018.06.274 - DOI
    1. Chen, D., Kannan, K., Tan, H., Zheng, Z., Feng, Y.-L., Wu, Y., & Widelka, M. (2016). Bisphenol analogues other than BPA: Environmental occurrence, human exposure, and toxicity—A review. Environmental Science and Technology, 50(11), 5438–5453. https://doi.org/10.1021/ACS.EST.5B05387 - DOI
    1. Cydzik-Kwiatkowska, A., Bernat, K., Zielińska, M., Bułkowska, K., & Wojnowska-Baryła, I. (2017). Aerobic granular sludge for bisphenol A (BPA) removal from wastewater. International Biodeterioration & Biodegradation, 122, 1–11. https://doi.org/10.1016/J.IBIOD.2017.04.008 - DOI

LinkOut - more resources