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. 2022 Nov 8;328(18):1866-1869.
doi: 10.1001/jama.2022.14914.

Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019

Calvin Ke  1 , Lorraine L Lipscombe  1 , Alanna Weisman  1 , Limei Zhou  2 , Peter C Austin  2 , Baiju R Shah  1 , Gillian L Booth  1
Affiliations

Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019

Calvin Ke et al. JAMA. .
No abstract available

Plain language summary

This study uses administrative health care data from Ontario, Canada, to assess whether changes in diabetes management practices have affected trends in the association between diabetes vs prior cardiovascular disease and risk of cardiovascular events from 1994 to 2019 among adults aged 20 to 84 years.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Ke reported receiving personal fees from Abbott, Sanofi, and AstraZeneca. Dr Lipscombe reported receiving grants from Novo Nordisk Foundation in the form of a donation to University of Toronto. No other disclosures were reported.

Figures

Figure.
Figure.. Trends in the Standardized Event Rate and Adjusted Relative Risk of Cardiovascular Events
Cardiovascular events were defined as acute myocardial infarction, stroke, or all-cause mortality. Results are stratified by diabetes and prior cardiovascular disease (CVD) at baseline. A, Event rates were standardized by age and sex to the 2021 population of Ontario, Canada. B, Five-year relative risks were computed using individuals with no diabetes or CVD as the reference group, adjusting for age, sex, and socioeconomic status.
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