Intra-season waning of immunity following the seasonal influenza vaccine in early and late vaccine recipients

doi:10.1016/j.jinf.2022.10.011

Comment

. 2022 Dec;85(6):e172-e174.

doi: 10.1016/j.jinf.2022.10.011. Epub 2022 Oct 13.

Intra-season waning of immunity following the seasonal influenza vaccine in early and late vaccine recipients

Affiliations

¹ Department of Respiratory Sciences, University of Leicester, UK; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
² The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
³ Department of Occupational Health, University Hospitals of Leicester NHS Trust, Leicester, UK.
⁴ Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
⁵ Department of Respiratory Sciences, University of Leicester, UK; Department of Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: julian.tang@uhl-tr.nhs.uk.
⁶ Department of Respiratory Sciences, University of Leicester, UK; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: mp426@le.ac.uk.

PMID: 36243199
PMCID: PMC9556766
DOI: 10.1016/j.jinf.2022.10.011

Comment

Intra-season waning of immunity following the seasonal influenza vaccine in early and late vaccine recipients

Joshua Nazareth et al. J Infect. 2022 Dec.

. 2022 Dec;85(6):e172-e174.

doi: 10.1016/j.jinf.2022.10.011. Epub 2022 Oct 13.

Authors

Affiliations

¹ Department of Respiratory Sciences, University of Leicester, UK; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
² The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
³ Department of Occupational Health, University Hospitals of Leicester NHS Trust, Leicester, UK.
⁴ Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
⁵ Department of Respiratory Sciences, University of Leicester, UK; Department of Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: julian.tang@uhl-tr.nhs.uk.
⁶ Department of Respiratory Sciences, University of Leicester, UK; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: mp426@le.ac.uk.

PMID: 36243199
PMCID: PMC9556766
DOI: 10.1016/j.jinf.2022.10.011

No abstract available

Keywords: Health care workers; Inactivated influenza vaccine; Waning immunity.

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Conflict of interest statement

Declaration of Competing Interest SGS declares an NIH grant, OptumLabs research credits, participation in Advisory Boards for influenza vaccines for Seqiris and Sanofi (no remuneration received), member of the WHO Strategic Advisory Group of Experts (SAGE) on Immunization Working Group on Influenza, and invited member of the National Influenza Surveillance Committee. IB declares shares in an influenza vaccine manufacturing company. MP declares research grants paid to institution from UKRI-MRC, NIHR and Gilead Sciences, and consulting fees from QIAGEN.

Figures

**Fig. 1**
GMT HAI titres with 95% confidence intervals for early and late vaccine recipients during the 2020/21 influenza season.

See this image and copyright information in PMC

Comment on

Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers.
Worsley CM, van der Mescht MA, Hoffmann D, Meyer PWA, Ueckermann V, Rossouw TM. Worsley CM, et al. J Infect. 2022 Sep;85(3):334-363. doi: 10.1016/j.jinf.2022.06.008. Epub 2022 Jun 12. J Infect. 2022. PMID: 35705136 Free PMC article. No abstract available.

Cited by

Immunogenicity of concomitant SARS-CoV-2 and influenza vaccination in UK healthcare workers: a prospective longitudinal observational study.
Nazareth J, Martin CA, Pan D, Barr IG, Sullivan SG, Peck H, Veli N, Das M, Bryant L, George N, Gohar M, Gray LJ, Teece L, Vail D, Renals V, Karia A, Renals P, Moss P, Tattersall A, Otter AD, Haldar P, Cooper A, Stephenson I, Wiselka MJ, Tang JW, Nellums L, Pareek M. Nazareth J, et al. Lancet Reg Health Eur. 2024 Aug 12;44:101022. doi: 10.1016/j.lanepe.2024.101022. eCollection 2024 Sep. Lancet Reg Health Eur. 2024. PMID: 39444701 Free PMC article.

References

1. Worsley C.M., van der Mescht M.A., Hoffmann D., Meyer P.W.A., Ueckermann V., Rossouw T.M. Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers. J Infect. 2022;85(3):334–363. - PMC - PubMed
1. Kissling E., Valenciano M., Larrauri A., Oroszi B., Cohen J.M., Nunes B., et al. Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case–control study. Eurosurveillance. 2013;18(5):20390. - PubMed
1. World Health Organization = Organisation mondiale de la S Weekly Epidemiological Record, 2020, vol. 95, 12 [full issue] Weekly Epidemiological Record. 2020;95(12):105–116.
1. World Health O . World Health Organization; Geneva: 2011. Manual for the laboratory diagnosis and virological surveillance of influenza.
1. (CPMP) ECfPMP . The European Agency for the Evaluation of Medicinal Products; London, UK: 1997. Note for guidance on harmonisation of requirements for influenza vaccines.

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[1] Worsley C.M., van der Mescht M.A., Hoffmann D., Meyer P.W.A., Ueckermann V., Rossouw T.M. Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers. J Infect. 2022;85(3):334–363. - PMC - PubMed

[2] Worsley C.M., van der Mescht M.A., Hoffmann D., Meyer P.W.A., Ueckermann V., Rossouw T.M. Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers. J Infect. 2022;85(3):334–363. - PMC - PubMed

[3] Kissling E., Valenciano M., Larrauri A., Oroszi B., Cohen J.M., Nunes B., et al. Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case–control study. Eurosurveillance. 2013;18(5):20390. - PubMed

[4] Kissling E., Valenciano M., Larrauri A., Oroszi B., Cohen J.M., Nunes B., et al. Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case–control study. Eurosurveillance. 2013;18(5):20390. - PubMed

[5] World Health Organization = Organisation mondiale de la S Weekly Epidemiological Record, 2020, vol. 95, 12 [full issue] Weekly Epidemiological Record. 2020;95(12):105–116.

[6] World Health Organization = Organisation mondiale de la S Weekly Epidemiological Record, 2020, vol. 95, 12 [full issue] Weekly Epidemiological Record. 2020;95(12):105–116.

[7] World Health O . World Health Organization; Geneva: 2011. Manual for the laboratory diagnosis and virological surveillance of influenza.

[8] World Health O . World Health Organization; Geneva: 2011. Manual for the laboratory diagnosis and virological surveillance of influenza.

[9] (CPMP) ECfPMP . The European Agency for the Evaluation of Medicinal Products; London, UK: 1997. Note for guidance on harmonisation of requirements for influenza vaccines.

[10] (CPMP) ECfPMP . The European Agency for the Evaluation of Medicinal Products; London, UK: 1997. Note for guidance on harmonisation of requirements for influenza vaccines.

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Intra-season waning of immunity following the seasonal influenza vaccine in early and late vaccine recipients

Affiliations

Intra-season waning of immunity following the seasonal influenza vaccine in early and late vaccine recipients

Authors

Affiliations

Conflict of interest statement

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Comment on

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