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. 2022 Dec;4(2):121-123.
doi: 10.1016/j.jobb.2022.08.001. Epub 2022 Aug 26.

Heat inactivation of monkeypox virus

Christophe Batéjat  1 , Quentin Grassin  1 , Maxence Feher  1 , Damien Hoinard  1 , Jessica Vanhomwegen  1 , Jean-Claude Manuguerra  1 , India Leclercq  1
Affiliations

Heat inactivation of monkeypox virus

Christophe Batéjat et al. J Biosaf Biosecur. 2022 Dec.

Abstract

Different kinds of media spiked with monkeypox virus (MPXV) were subjected to heat inactivation at different temperatures for various periods of time. The results showed that MPXV was inactivated in less than 5 min at 70 °C and less than 15 min at 60 °C, with no difference between viruses from the West African and Central African clades. The present findings could help laboratory workers to manipulate MPXV in optimal biosafety conditions and improve their protocols.

Keywords: Heat; Inactivation; Monkeypoxvirus; Virus.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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