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. 2022 Sep 30:13:988264.
doi: 10.3389/fgene.2022.988264. eCollection 2022.

Genetic sources and loci for Fusarium head blight resistance in bread wheat

Lei Wu  1 , Xinyao He  2 , Yi He  1 , Peng Jiang  1 , Kaijie Xu  3 , Xu Zhang  1 , Pawan K Singh  2
Affiliations

Genetic sources and loci for Fusarium head blight resistance in bread wheat

Lei Wu et al. Front Genet. .

Abstract

Fusarium head blight (FHB) of wheat is an important disease worldwide, affecting the yield, end-use quality and threatening food safety. Genetic resources or stable loci for FHB resistance are still limited in breeding programs. A panel of 265 bread wheat accessions from China, CIMMYT-Mexico and other countries was screened for FHB resistance under 5 field experiments in Mexico and China, and a genome-wide association analysis was performed to identify QTLs associated with FHB resistance. The major locus Fhb1 was significantly associated with FHB severity and Deoxynivalenol content in grains. FHB screening experiments in multiple environments showed that Fhb1-harbouring accessions Sumai3, Sumai5, Ningmai9, Yangmai18 and Tokai66 had low FHB index, disease severity and DON content in grains in response to different Fusarium species and ecological conditions in Mexico and China. Accessions Klein Don Enrique, Chuko and Yumai34 did not have Fhb1 but still showed good FHB resistance and low mycotoxin accumulation. Sixteen loci associated with FHB resistance or DON content in grains were identified on chromosomes 1A, 1B, 2B, 3A, 3D, 4B, 4D, 5A, 5B, 7A, and 7B in multiple environments, explaining phenotypic variation of 4.43-10.49%. The sources with good FHB resistance reported here could be used in breeding programs for resistance improvement in Mexico and China, and the significant loci could be further studied and introgressed for resistance improvement against FHB and mycotoxin accumulation in grains.

Keywords: Fusarium head blight; deoxynivalenol; genetic sources; genome-wide association study; resistance.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Frequency distribution of FHB index (A), number of diseased spikelets (C and D) and DON content in grains (B and E) based on the mean data in Mexico (MX, spray inoculation) and China (CN, point and spawn inoculation).
FIGURE 2
FIGURE 2
Distributions of FHB index, number of diseased spikelets and DON content among different groups. (A) Distribution of mean data of FHB index using spray inoculation among different groups in 2018 and 2019 in Mexico. (B) Distribution of mean data of DON content using spray inoculation among different groups in 2018 and 2019 in Mexico. (C) Distribution of mean data of FHB severity using point inoculation among different groups in 2018, 2019 and 2020 in China. (D) Distribution of mean data of FHB severity using spawn inoculation among different groups in 2018 and 2019 in China. (E) Distribution of mean data of DON content in grains using point inoculation among different groups in 2018, 2019 and 2020 in China.
FIGURE 3
FIGURE 3
Differences in FHB index (A), number of diseased spikelets (C and D) and DON content (B and E) between Fhb1 and non-Fhb1 accessions.
FIGURE 4
FIGURE 4
Manhattan plots showing SNPs associated with number of diseased spikelets using point inoculation (A) and spawn inoculation (B), and those for DON content using point inoculation (C) in China.
FIGURE 5
FIGURE 5
Manhattan plots showing SNPs associated with FHB index using spray inoculation (A) and those for DON content (B) using spray inoculation in Mexico.
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