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Case Reports
. 2022 Dec 20;39(6):1427-1431.
doi: 10.20960/nh.04003.

[Oral desensitization with Ketocal® in an infant with ketogenic diet and cow's milk protein allergy]

[Article in Spanish]
Cristina Benítez Provedo  1 , María Angeles Martínez Ibeas  2 , Rebeca Losada Del Pozo  3 , Ana María Montes Arjona  4 , Miriam Blanco Rodríguez  2 , Genoveva Del Río Camacho  5
Affiliations
Free article
Case Reports

[Oral desensitization with Ketocal® in an infant with ketogenic diet and cow's milk protein allergy]

[Article in Spanish]
Cristina Benítez Provedo et al. Nutr Hosp. .
Free article

Abstract
in English, Spanish

Introduction: ketogenic diet is a treatment with proven efficacy in drug-refractory childhood epilepsy. Cow's milk protein allergy may be a limitation for treating infants with ketogenic diet, as they need a product that contains cow's milk protein (Ketocal®). Case report: we report the case of an infant with a drug-refractory epileptic encephalopathy and IgE-mediated cow's milk protein allergy, who started a classic ketogenic diet. Oral desensitization was achieved with Ketocal 3:1®, allowing its use in the diet and achieving a clinical improvement with seizure control. Discussion: a patient with epilepsy and cow's milk protein allergy can benefit from the ketogenic diet, since it is possible to perform an oral immunotherapy with Ketocal®, also achieving a probable resolution of his/her allergy.

Introducción: la dieta cetogénica es un tratamiento con eficacia demostrada en la epilepsia infantil refractaria a fármacos. La alergia a la proteína de leche de vaca puede ser una limitación para tratar a lactantes con dieta cetogénica, ya que necesitan un producto que contiene proteínas de leche de vaca (Ketocal®). Caso clínico: presentamos el caso de un lactante con una encefalopatía epiléptica refractaria a fármacos y alergia a las proteínas de leche de vaca IgE mediada al que se quiere instaurar una dieta cetogénica clásica. Se consigue la desensibilización con Ketocal 3:1®, pudiendo utilizarlo en la dieta y logrando una mejoría clínica con el control de las crisis. Discusión: un paciente con epilepsia y alergia a las proteínas de leche de vaca puede beneficiarse de la dieta cetogénica, ya que es posible realizar una inmunoterapia oral con Ketocal® y conseguir, además, una probable resolución de su alergia.

Keywords: Dieta cetogénica. Alergia a proteínas de leche de vaca. Inmunoterapia oral..

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