BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection

Christina A Clarke¹, Kathryn Lang², Girish Putcha³, Jonathan P Beer⁴, Maude Champagne⁵, Andrea Ferris⁶, James H Godsey⁷, Robert L Grossman⁸, Jody M Hoyos⁹, Donald J Johann¹⁰, Nancy Krunic⁴, Peter Kuhn¹¹, Jerry S H Lee¹¹, Tara Maddala¹², Marielena Mata¹³, Jeremiah McDole¹⁴, Omar Perez¹⁵, Howard Scher¹⁶, Mark D Stewart¹⁷, Seema Singh Bhan¹⁸, Qu Zhang¹⁹, Lauren C Leiman²⁰

Affiliations

¹ GRAIL LLC, Menlo Park, California, USA.
² Guardant Health, Redwood City, California, USA.
³ Freenome, South San Francisco, California, USA.
⁴ Novartis, Cambridge, Massachusetts, USA.
⁵ Illumina, San Diego, California, USA.
⁶ Lungevity Foundation, Bethesda, Maryland, USA.
⁷ Quest Diagnostics, Irvine, California, USA.
⁸ Open Commons Consortium, Chicago, Illinois, USA.
⁹ Prevent Cancer Foundation, Alexandria, Virginia, USA.
¹⁰ University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
¹¹ University of Southern California, Los Angeles, California, USA.
¹² Delfi Diagnostics, Palo Alto, California, USA.
¹³ Pfizer, San Diego, California, USA.
¹⁴ Bio-Rad Laboratories Inc, Digital Biology Group, Pleasanton, California, USA.
¹⁵ AstraZeneca, Gaithersburg, Maryland, USA.
¹⁶ Memorial Sloan Kettering Cancer Center, New York, New York, USA.
¹⁷ Friends of Cancer Research, Washington, DC, USA.
¹⁸ EXACT Sciences, Madison, Wisconsin, USA.
¹⁹ GlaxoSmithKline, Collegeville, Pennsylvania, USA.
²⁰ BLOODPAC, Chicago, Illinois, USA.

PMID: 36251491
PMCID: PMC9841293
DOI: 10.1111/cts.13427

BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection

Christina A Clarke et al. Clin Transl Sci. 2023 Jan.

. 2023 Jan;16(1):5-9.

doi: 10.1111/cts.13427. Epub 2022 Oct 17.

Authors

Affiliations

¹ GRAIL LLC, Menlo Park, California, USA.
² Guardant Health, Redwood City, California, USA.
³ Freenome, South San Francisco, California, USA.
⁴ Novartis, Cambridge, Massachusetts, USA.
⁵ Illumina, San Diego, California, USA.
⁶ Lungevity Foundation, Bethesda, Maryland, USA.
⁷ Quest Diagnostics, Irvine, California, USA.
⁸ Open Commons Consortium, Chicago, Illinois, USA.
⁹ Prevent Cancer Foundation, Alexandria, Virginia, USA.
¹⁰ University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
¹¹ University of Southern California, Los Angeles, California, USA.
¹² Delfi Diagnostics, Palo Alto, California, USA.
¹³ Pfizer, San Diego, California, USA.
¹⁴ Bio-Rad Laboratories Inc, Digital Biology Group, Pleasanton, California, USA.
¹⁵ AstraZeneca, Gaithersburg, Maryland, USA.
¹⁶ Memorial Sloan Kettering Cancer Center, New York, New York, USA.
¹⁷ Friends of Cancer Research, Washington, DC, USA.
¹⁸ EXACT Sciences, Madison, Wisconsin, USA.
¹⁹ GlaxoSmithKline, Collegeville, Pennsylvania, USA.
²⁰ BLOODPAC, Chicago, Illinois, USA.

PMID: 36251491
PMCID: PMC9841293
DOI: 10.1111/cts.13427

No abstract available

PubMed Disclaimer

Conflict of interest statement

C.A.C. is an employee of GRAIL and Illumina shareholder. G.P. is a former employee an shareholder of Freenome. J.P.B. is an employee and shareholder of Novartis. M.C. is an employee and shareholder of Illumina. N.K. is an employee and shareholder of Novartis. T.M. is a former employee and shareholder of Delfi and an Illumina shareholder as well. M.M. is an employee and shareholder of Pfizer. S.S.B. is an employee and shareholder of EXACT Sciences. Q.Z. is an employee and shareholder of GlaxoSmithKline. All other authors declared no competing interests for this work.

References

1. Clarke CA, Hubbell E, Kurian AW, Colditz GA, Hartman A‐R, Gomez SL. Projected reductions in absolute cancer–related deaths from diagnosing cancers before metastasis, 2006–2015. Cancer Epidemiol Biomarkers Prev. 2020;29(5):895 LP‐902. doi:10.1158/1055-9965.EPI-19-1366 - DOI - PubMed
1. NCI Cancer Stat Facts: Cervical Cancer. Accessed July 2022. https://seer.cancer.gov/statfacts/html/cervix.html
1. Ilic D, Djulbegovic M, Jung JH, et al. Prostate cancer screening with prostate‐specific antigen (PSA) test: a systematic review and meta‐analysis. BMJ. 2018;362:k3519. doi:10.1136/bmj.k3519 - DOI - PMC - PubMed
1. Horn DM, Haas JS. Expanded lung and colorectal cancer screening—ensuring equity and safety under new guidelines. N Engl J Med. 2022;386(2):100‐102. doi:10.1056/NEJMp2113332 - DOI - PubMed
1. Putcha G, Gutierrez A, Skates S. Multicancer screening: one size does not fit all. JCO Precis Oncol. 2021;5:574‐576. doi:10.1200/PO.20.00488 - DOI - PubMed

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BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection

Affiliations

BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection

Authors

Affiliations

Conflict of interest statement

References

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