Spontaneous Intestinal Perforation of the Newborn
- PMID: 36251805
- Bookshelf ID: NBK585031
Spontaneous Intestinal Perforation of the Newborn
Excerpt
Spontaneous intestinal perforation of the newborn, also known as focal intestinal perforation or isolated perforation, is a single intestinal perforation typically occurring at the terminal ileum. It is a life-threatening condition that affects very low birth weight infants (birth weight <1500 g) and deficient birth weight infants (birth weight <1000 g).
Spontaneous intestinal perforation is associated with high morbidity and mortality. The perforation location is most commonly focal and involves the antimesenteric border of the terminal ileum. The jejunum and colon are other possible locations for spontaneous intestinal perforation.
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Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Prognosis
- Complications
- Postoperative and Rehabilitation Care
- Consultations
- Deterrence and Patient Education
- Pearls and Other Issues
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
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    - Ragouilliaux CJ, Keeney SE, Hawkins HK, Rowen JL. Maternal factors in extremely low birth weight infants who develop spontaneous intestinal perforation. Pediatrics. 2007 Dec;120(6):e1458-64. - PubMed
 
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    - Nakajima Y, Masaoka N, Yamamoto T. Obstetrical risk factors for focal intestinal perforation in very low birth weight infants. J Perinat Med. 2011 Mar;39(2):179-84. - PubMed
 
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    - Tanaka Y, Uchida H, Kawashima H, Sato K, Takazawa S, Deie K, Masuko T, Kanno K, Shimizu M. Influence of surgical intervention on neurodevelopmental outcome in infants with focal intestinal perforation. Pediatr Int. 2015 Aug;57(4):687-9. - PubMed
 
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    - Eicher C, Seitz G, Bevot A, Moll M, Goelz R, Arand J, Poets C, Fuchs J. Surgical management of extremely low birth weight infants with neonatal bowel perforation: a single-center experience and a review of the literature. Neonatology. 2012;101(4):285-92. - PubMed
 
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