Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Dec 1;37(6):829-835.
doi: 10.21470/1678-9741-2021-0621.

Early Mortality Predictors in İnfective Endocarditis Patients: A Single-Center Surgical Experience

Çiğdem Tel Üstünışık  1 , Zihni Mert Duman  2 , Barış Timur  3 , Timuçin Aksu  4 , Taner İyigün  4 , Safa Göde  4 , Muhammed Bayram  4 , Vedat Erentuğ  4
Affiliations

Early Mortality Predictors in İnfective Endocarditis Patients: A Single-Center Surgical Experience

Çiğdem Tel Üstünışık et al. Braz J Cardiovasc Surg. .

Abstract

Introduction: Infective endocarditis is a disease that progresses with morbidity and mortality, afecting 3-10 out of 100,000 people per year. We conducted this study to review the early outcomes of surgical treatment of infective endocarditis.

Methods: In this retrospective study, 122 patients who underwent cardiac surgery for infective endocarditis in our clinic between November 2009 and December 2020 were evaluated. Patients were divided into two groups according to in-hospital mortality. Demographic, echocardiographic, laboratory, operative, and postoperative data of the groups were compared.

Results: Between November 3, 2009, and December 7, 2020, 122 patients were operated for infective endocarditis in our hospital. Emergency surgery was performed in nine (7.3%) patients. In-hospital mortality occurred in 23 (18.9%) patients, and 99 (81.1%) patients were discharged. In-hospital mortality was related with older age, presence of periannular abscess, New York Heart Association class 3 or 4 symptoms, low albumin level, high alanine aminotransferase level, and longer cross-clamping time (P<0.05 for all).

Conclusion: The presence of paravalvular abscess was the most important prognostic factor in patients operated for infective endocarditis.

Keywords: Abscess; Alanine Transaminase; Endocarditis; Hospital Mortality; Mortality; Thoracic Surgery.

PubMed Disclaimer

Conflict of interest statement

No conflict of interest.

Comment in

References

    1. Cahill TJ, Prendergast BD. Infective endocarditis. Lancet. 2016;387(10021):882–893. doi: 10.1016/S0140-6736(15)00067-7. - DOI - PubMed
    1. Habib G, Erba PA, Iung B, Donal E, Cosyns B, Laroche C, et al. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: a prospective cohort study. Eur Heart J. 2019;40(39):3222–3232. doi: 10.1093/eurheartj/ehz620. Erratum in: Eur Heart J. 2020;41(22):2091. - DOI - PubMed
    1. Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, et al. 2015 ESC guidelines for the management of infective endocarditis: the task force for the management of infective endocarditis of the European society of cardiology (ESC). Endorsed by: European association for cardio-thoracic surgery (EACTS), the European association of nuclear medicine (EANM) Eur Heart J. 2015;36(44):3075–3128. doi: 10.1093/eurheartj/ehv319. - DOI - PubMed
    1. Garg P, Ko DT, Bray Jenkyn KM, Li L, Sharif SZ. Infective endocarditis hospitalizations and antibiotic prophylaxis rates before and after the 2007 American heart association guideline revision. Circulation. 2019;140(3):170–180. doi: 10.1161/CIRCULATIONAHA.118.037657. - DOI - PubMed
    1. Papakonstantinou PE, Samonis G, Andrianaki AM, Christofaki M, Dimopoulou D, Papadakis J, et al. Epidemiology, microbiological and clinical features, treatment, and outcomes of infective endocarditis in Crete, Greece. Infect Chemother. 2018;50(1):21–28. doi: 10.3947/ic.2018.50.1.21. - DOI - PMC - PubMed

LinkOut - more resources