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Comment
. 2022 Dec 1;158(12):1436-1437.
doi: 10.1001/jamadermatol.2022.4543.

Systemic Interventions for Treatment of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Summary of a Cochrane Review

Megan H Noe  1 , Robert G Micheletti  2
Affiliations
Comment

Systemic Interventions for Treatment of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Summary of a Cochrane Review

Megan H Noe et al. JAMA Dermatol. .

Abstract

Clinical question: What are the effects of systemic therapies for Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)?

Bottom line: There is limited high-quality evidence to support the use of systemic immunomodulatory therapies to decrease mortality rates in SJS/TEN.

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