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. 2023 Jan;95(1):e28242.
doi: 10.1002/jmv.28242. Epub 2022 Oct 28.

Evidence for human infection with avian influenza A(H9N2) virus via environmental transmission inside live poultry market in Xiamen, China

Yifei Jin  1 , Huan Cui  2 , Lina Jiang  3 , Cheng Zhang  2 , Jingjing Li  1 , Hongliang Cheng  1 , Zehui Chen  3 , Jing Zheng  3 , Yidun Zhang  3 , Yingying Fu  1 , Jiaming Li  1 , Li Li  3 , Zhendong Guo  2 , Bing Lu  1 , Zhongyi Wang  1
Affiliations

Evidence for human infection with avian influenza A(H9N2) virus via environmental transmission inside live poultry market in Xiamen, China

Yifei Jin et al. J Med Virol. 2023 Jan.

Abstract

H9N2 avian influenza virus (AIV) has become prevalent in the live poultry market (LPM) worldwide, and environmental transmission mode is an important way for AIVs to infect human beings in the LPM. To find evidence of human infection with the influenza A(H9N2) virus via environmental contamination, we evaluated one human isolate and three environmental isolates inside LPMs in Xiamen, China. The phylogeny, transmissibility, and pathogenicity of the four isolates were sorted out systematically. As for the H9N2 virus, which evolved alongside the "Avian-Environment-Human" spreading chain in LPMs from the summer of 2019 to the summer of 2020, its overall efficiency of contact and aerosol transmissibility improved, which might contribute to the increasing probability of human infection. This study indicated that environmental exposure might act as an important source of human infection in LPMs.

Keywords: H9N2; environmental transmission; evolution low; human infection; live poultry market.

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References

REFERENCES

    1. Peiris M, Yuen KY, Leung CW, et al. Human infection with influenza H9N2. Lancet. 1999;354(9182):916-917.
    1. European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC), European Reference Laboratory for Avian Influenza (EURL), et al. 2022. Scientific report: Avian influenza overview December 2021 - March 2022. EFSA Journal. 20(4):7289. doi:10.2903/j.efsa.2022.7289
    1. Influenza Risk Assessment Tool (IRAT) - Virus Report-Influenza A(H9N2) virus from the US CDC. https://www.cdc.gov/flu/pandemic-resources/pdf/IR-001Rev0D-CDC-IRAT-Viru...
    1. Bi Y, Li J, Li S, et al. Dominant subtype switch in avian influenza viruses during 2016-2019 in China. Nat Commun. 2020;11(1):5909.
    1. Liu D, Shi W, Gao GF. Poultry carrying H9N2 act as incubators for novel human avian influenza viruses. Lancet. 2014;383(9920):869.

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