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. 2023 Feb;47(2):510-518.
doi: 10.1007/s00268-022-06806-4. Epub 2022 Oct 20.

Kidney Transplantation and Obesity: Are There Any Differences in Outcomes?

Mahmoudreza Moein  1 , Melanie Tacher Otero  1 , Gavrielle J Rood  1 , Matthew Hanlon  1 , Reza Saidi  2
Affiliations

Kidney Transplantation and Obesity: Are There Any Differences in Outcomes?

Mahmoudreza Moein et al. World J Surg. 2023 Feb.

Abstract

Introduction: Kidney transplantation (KT) is the gold standard treatment for end-stage renal disease (ESRD) patients. Obesity is a strong risk factor for developing cardiovascular disease, chronic kidney disease, and ESRD. This study aimed to investigate the outcomes of kidney transplantation in obese recipients.

Material and methods: We retrospectively reviewed the medical records of recipients from January 2016 to December 2021 in a single center. Outcomes in recipients of a kidney allograft with BMI ≥ 30 were compared with the outcomes in recipients with 30 < BMI.

Results: A total of 467 consecutive kidney transplantation recipients' files were studied. 213 (45.6%) allograft recipients had a BMI ≥ 30, and 254 (54.4%) allograft recipients had a BMI < 30. DGF rate was 29.1% in the BMI ≥ 30 and 30.7% in the BMI < 30 group (P = 0.41). On the other hand, 30 days readmission rate also did not show a significant difference between the BMI ≥ 30 and BMI < 30 allograft recipients (37 vs. 33.8%, P = 0.46). The mean overall costs of transplantation in the BMI ≥ 30 group was $254,395, and it was $256,029 in the BMI < 30 group (P = 0.84).

Conclusion: Our study shows that the outcomes of renal allograft transplant were comparable between recipients with BMI ≥ 30 and BMI < 30 in terms of DGF, LOS, 30 days readmission, acute rejection rate, and survival rates, and BMI should not be a single independent criterion for decision making to select an optimal recipient.

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References

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