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Review
. 2022 Oct 20;74(1):77.
doi: 10.1186/s43044-022-00317-2.

Emerging biomarkers for the detection of cardiovascular diseases

Sreenu Thupakula  1 , Shiva Shankar Reddy Nimmala  1 , Haritha Ravula  2 , Sudhakar Chekuri  3 , Raju Padiya  4
Affiliations
Review

Emerging biomarkers for the detection of cardiovascular diseases

Sreenu Thupakula et al. Egypt Heart J. .

Abstract

Background: The prevalence of cardiovascular disease (CVD) has been continuously increasing, and this trend is projected to continue. CVD is rapidly becoming a significant public health issue. Every year there is a spike in hospital cases of CVD, a critical health concern in lower- and middle-income countries. Based on identification of novel biomarkers, it would be necessary to study and evaluate the diagnostic requirements or CVD to expedite early detection.

Main body: The literature review was written using a wide range of sources, such as well-known medical journals, electronic databases, manuscripts, texts, and other writings from the university library. After that, we analysed the specific markers of CVD and compiled a systematic review. A growing body of clinical research aims to identify people who are at risk for cardiovascular disease by looking for biomolecules. A small number of biomarkers have been shown to be useful and reliable in medicine. Biomarkers can be used for a variety of clinical applications, such as predicting heart disease risk, diagnosing disease, or predicting outcomes. As a result of the ability for a single molecule to act as a biomarker, its usefulness in medicine is expected to increase significantly.

Conclusions: Based on assessing the current trends in the application of CVD markers, we discussed and described the requirements for the application of CVD biomarkers in coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other cardiovascular illnesses. Furthermore, the current review focuses on biomarkers for CVD and the procedures that should be considered to establish the comprehensive nature of the expression of biomarkers for cardiovascular illness.

Keywords: Biomarkers; Biomolecular systems; Cardiac markers; Cardiovascular disease; Diagnosis; Therapeutics.

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Conflict of interest statement

None of the other authors has any conflicts of interest, financial or otherwise, to disclose.

Figures

Fig. 1
Fig. 1
Schematic illustration of emerging biomarkers for the cardiovascular diseases respective to the biomolecular information currently available in the literature
See this image and copyright information in PMC

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