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Review
. 2022 Nov;42(4):743-760.
doi: 10.1016/j.iac.2022.05.005. Epub 2022 Sep 24.

Environmental Exposures Impact Pediatric Asthma Within the School Environment

Caroline L Mortelliti  1 , Tina M Banzon  1 , Carolina Zilli Vieira  2 , Wanda Phipatanakul  3
Affiliations
Review

Environmental Exposures Impact Pediatric Asthma Within the School Environment

Caroline L Mortelliti et al. Immunol Allergy Clin North Am. 2022 Nov.

Abstract

The school is a microenvironment well-known to host many indoor allergens and pollutants, with a strong association between school allergen exposure and childhood asthma morbidity. Despite advances in therapies, asthma continues to be one of the most common chronic conditions among children, associated with significant morbidity, health care utilization, and productivity loss. Asthma prevalence is also disproportionately high among children in minority communities. This review will focus on environmental exposures associated with asthma morbidity (cockroach, mouse, cat and dog, dust mite, fungus, air pollution). This review will also discuss recent school-based interventions to improve allergy morbidity among school-aged children. Understanding the multifaceted environmental factors which may contribute to asthma pathogenesis is necessary to help guide potential school-based interventions.

Keywords: Allergen exposure; Childhood asthma; HEPA filter; Indoor allergens; Integrated pest management; Pediatrics; School inner-city asthma study (SICAS); School-based interventions.

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Conflict of interest statement

Acknowledgments Grant IDs:1. 5K24AI106822 2. 5U01AI126614 3. 5R01HL137192 4. 5UO1AI1103975. Co-Author Tina Banzon also has a NIH T32 grant which should be placed on the cover: NIH T32 AI7512-35. Disclosure All authors do not have any financial and personal relationships with other people or organizations that could influence (bias) their work. The authors have no disclosures of any affiliation with any organization with a financial interest, direct or indirect, in the subject matter or materials discussed in the article (such as consultancies, employment, paid expert testimony, honoraria, speaker’s bureaus, retainers, stock options or ownership, patents or patent applications or travel grants) that may affect the conduct or reporting of the work submitted.

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