Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2022 Oct;11(5):762-765.
doi: 10.21037/hbsn-22-390.

Advancing proteomics and machine learning in the clinic: an editorial on " Noninvasive proteomic biomarkers for alcohol-related liver disease"

Courtney D McGinnis  1 , Brenton I M Graham  1 , Peter S Harris  1 , Kristofer S Fritz  1
Affiliations
Editorial

Advancing proteomics and machine learning in the clinic: an editorial on " Noninvasive proteomic biomarkers for alcohol-related liver disease"

Courtney D McGinnis et al. Hepatobiliary Surg Nutr. 2022 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.com/article/view/10.21037/hbsn-22-390/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Schematic model of the bioinformatic and machine learning approach utilized to identify and validate clinically relevant biomarkers in hepatic biopsies and serum samples of patients with ALD. ALD, alcohol-associated liver disease. ROC, receiver operating characteristic; AUC, area under the curve.
See this image and copyright information in PMC

Comment on

  • Noninvasive proteomic biomarkers for alcohol-related liver disease.
    Niu L, Thiele M, Geyer PE, Rasmussen DN, Webel HE, Santos A, Gupta R, Meier F, Strauss M, Kjaergaard M, Lindvig K, Jacobsen S, Rasmussen S, Hansen T, Krag A, Mann M. Niu L, et al. Nat Med. 2022 Jun;28(6):1277-1287. doi: 10.1038/s41591-022-01850-y. Epub 2022 Jun 2. Nat Med. 2022. PMID: 35654907 Free PMC article.

References

    1. Singal AK, Kwo P, Kwong A, et al. Research methodologies to address clinical unmet needs and challenges in alcohol-associated liver disease. Hepatology 2022;75:1026-37. 10.1002/hep.32143 - DOI - PMC - PubMed
    1. World Health Organization. Management of Substance Abuse Team. Global status report on alcohol and health. Geneva, Switzerland: World Health Organization; 2011: xii, 286.
    1. Poole LG, Dolin CE, Arteel GE. Organ-Organ Crosstalk and Alcoholic Liver Disease. Biomolecules 2017;7:62. 10.3390/biom7030062 - DOI - PMC - PubMed
    1. Szabo G, Thursz M, Shah VH. Therapeutic advances in alcohol-associated hepatitis. J Hepatol 2022;76:1279-90. 10.1016/j.jhep.2022.03.025 - DOI - PubMed
    1. Schnabl B, Arteel GE, Stickel F, et al. Liver specific, systemic and genetic contributors to alcohol-related liver disease progression. Z Gastroenterol 2022;60:36-44. 10.1055/a-1714-9330 - DOI - PMC - PubMed