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Case Reports
. 2022 Sep 21:82:104752.
doi: 10.1016/j.amsu.2022.104752. eCollection 2022 Oct.

Primary Extraskeletal Ewing sarcoma of the foot with extensive skeletal and pulmonary metastasis: A rare case report

Oadi N Shrateh  1 , Afnan W M Jobran  1 , Haneen Owienah  2 , Thaer Sweileh  2 , Mohand Abulihya  3 , Motaz A Natsheh  3 , Nazeeh Abu-Dayyah  4
Affiliations
Case Reports

Primary Extraskeletal Ewing sarcoma of the foot with extensive skeletal and pulmonary metastasis: A rare case report

Oadi N Shrateh et al. Ann Med Surg (Lond). .

Abstract

Introduction: First -degree cutaneous extraskeletal Ewing's sarcomas (ESs) are incredibly uncommon skin-specific tumors that often present as a single, tiny lesion that is restricted to the mid-to-deep dermis or involves the subcutis. ESs can be clinically and pathologically misdiagnosed because of their rarity and physical resemblance to other cutaneous cancers.

Case presentation: A 47-year-old nonsmoking woman was admitted after being transferred from a nearby hospital to check her right foot pain that had been present for three months and was significantly numbing the same side. Only a few lone cases or brief series are reported in the current literature. The typical description of ESs is that they are tiny masses with positive clinical behavior.

Discussion: Despite being a rather common location, only infrequent and minor ESs of the foot are present. After the recommended operation and subsequent histology analysis, we identified this uncommon sort of tumors.

Conclusion: Although it's rare, it's very important to consider this tumor in the differential diagnosis of foot pain with/without visible and/or palpable cutaneous lesion.

Keywords: Case report; Cutaneous Ewing sarcoma; Extraskeletal Ewing sarcoma; Foot sarcoma.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this article.

Figures

Fig. 1
Fig. 1
(A): is a Computed Tomography (CT) scan with bone window, (B): is a CT scan with soft tissue window, and (C): is a CT scan with coronal view demonstrating para-spinal soft tissue lesion at the level of T8-T9, (Arrows define the significant findings).
Fig. 2
Fig. 2
(A): is a CT scan showing lytic lesions of the spine and sternum, (B): is a CT scan showing sclerotic and lytic lesions of the pelvis, and (C): is a CT scan showing metastatic lesion in the right lung, (Arrows define the significant findings).
Fig. 3
Fig. 3
(A): is a Magnetic resonance imaging (MRI) of right foot (RF) with T1-weighting, (B): is an MRI of RF with Short Tau Inversion Recovery (STIR) sequence, (C): is an MRI of RF with Proton density (PD) weighting, and (D): is an MRI of RF with T2-weighting, (Arrows define the significant findings).
Fig. 4
Fig. 4
(A): H & E stain, (B): CD99, (C): FLI-1, and (D): Anti NKx-2.2.
See this image and copyright information in PMC

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