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Review
. 2022 Nov;40(4):769-783.
doi: 10.1016/j.ncl.2022.03.008. Epub 2022 Sep 28.

Sleep and Epilepsy: Practical Implications

Madeleine M Grigg-Damberger  1 , Nancy Foldvary-Schaefer  2
Affiliations
Review

Sleep and Epilepsy: Practical Implications

Madeleine M Grigg-Damberger et al. Neurol Clin. 2022 Nov.

Abstract

Sleep is a restorative balm for many, often less so for people with epilepsy. Complex bidirectional interactions between sleep and epilepsy can be detrimental to sleep, epilepsy and those affected. Sleep is a state of variable activation of the EEG and seizure occurrence in people with epilepsy. Sleep disorders are highly prevalent and portend worse seizure and epilepsy-related outcomes. Randomized clinical trials of sleep interventions in epilepsy populations are few, yet warranted, given the effects of sleep dysfunction on quality of life and the risk of SUDEP in people with epilepsy.

Keywords: Antiseizure medications; Daytime sleepiness; Epilepsy; Insomnia; Obstructive sleep apnea; Sleep; Sleep disorders.

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