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Case Reports
. 2023 Mar;39(3):825-828.
doi: 10.1007/s00381-022-05703-4. Epub 2022 Oct 21.

Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle dysfunction syndrome (MSMDS)

Anthony Roylance  1 , Stefan Spinty  2 , Benedetta Pettorini  3
Affiliations
Case Reports

Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle dysfunction syndrome (MSMDS)

Anthony Roylance et al. Childs Nerv Syst. 2023 Mar.

Abstract

Multi-systemic smooth muscle dysfunction syndrome (MSMDS) is extremely rare and can manifest in multiple ways. Associated hydrocephalus has not yet been reported. Here, we report a three-year-old girl with communicating hydrocephalus and raised intracranial pressure secondary to MSMDS. Pathological mechanisms are proposed, as is the need to investigate patients diagnosed with MSMDS for ventriculomegaly and raised pressure.

Keywords: ACTA2; Leukomalacia; Ventriculomegaly.

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References

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