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. 2022 Oct 22;32(1):45.
doi: 10.1038/s41533-022-00311-w.

A systematic review of the effects of e-cigarette use on lung function

Lucy Honeycutt  1 , Katherine Huerne  1   2 , Alanna Miller  1 , Erica Wennberg  1 , Kristian B Filion  1   3 , Roland Grad  1   4 , Andrea S Gershon  5 , Carolyn Ells  1   2   4 , Genevieve Gore  6 , Andrea Benedetti  3   7 , Brett Thombs  1   3   8 , Mark J Eisenberg  9   10   11
Affiliations

A systematic review of the effects of e-cigarette use on lung function

Lucy Honeycutt et al. NPJ Prim Care Respir Med. .

Abstract

Given the increasing use of e-cigarettes and uncertainty surrounding their safety, we conducted a systematic review to determine the effects of e-cigarettes on measures of lung function. We systematically searched EMBASE, MEDLINE, and PsycINFO databases via Ovid, the Cochrane CENTRAL database, and the Web of Science Core from 2004 until July 2021, identifying 8856 potentially eligible studies. A total of eight studies (seven studying immediate effects and one long-term effects, 273 total participants) were included. The risk of bias was assessed using the Risk of Bias in Non-randomized Studies-of Interventions (ROBINS-I) and Cochrane risk of bias tools. These studies suggest that vaping increases airway resistance but does not appear to impact forced expiratory volume in one second (FEV1), forced vital capacity (FVC), or FEV1/FVC ratio. However, given the limited size and follow-up duration of these studies, larger, long-term studies are required to further determine the effects of e-cigarettes on lung function.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram of included studies assessing the effect of e-cigarettes on lung function.
See this image and copyright information in PMC

References

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