Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2022 Oct 22;21(1):202.
doi: 10.1186/s12943-022-01673-y.

Correction: Knockdown of SOX2OT inhibits the malignant biological behaviors of glioblastoma stem cells via up-regulating the expression of miR-194-5p and miR-122

Rui Su  1   2 , Shuo Cao  1   2 , Jun Ma  1   2 , Yunhui Liu  3   4   5 , Xiaobai Liu  3   4   5 , Jian Zheng  3   4   5 , Jiajia Chen  1   2 , Libo Liu  1   2 , Heng Cai  3   4   5 , Zhen Li  3   4   5 , Lini Zhao  1   2 , Qianru He  1   2 , Yixue Xue  6   7
Affiliations
Published Erratum

Correction: Knockdown of SOX2OT inhibits the malignant biological behaviors of glioblastoma stem cells via up-regulating the expression of miR-194-5p and miR-122

Rui Su et al. Mol Cancer. .
No abstract available

PubMed Disclaimer

Figures

Fig. 6
Fig. 6
SOX3 mediated tumor-suppressive effects of miR-194-5p and miR-122. a CCK8 assay to evaluate the effect of miR-194-5p and SOX3 on cell proliferation of GSC-U87 and GSC-U251 cells. b Flow cytometry analysis to evaluate the effect of miR-194-5p and SOX3 on cell apoptosis of GSC-U87 and GSC-U251 cells. c Transwell assay to evaluate the effect of miR-194-5p and SOX3 on the cell migration and invasion of GSC-U87 and GSC-U251 cells. Data are presented as the mean ± SD (n = 5, each group). Scale bars represent 40 μm. ** P < 0.01 vs. AgomiR-194-5p-NC + SOX3(+)NC group, ## P < 0.01 vs. AgomiR-194-5p + SOX3(+)NC group. d CCK8 assay to evaluate the effect of miR-122 and SOX3 on cell proliferation of GSC-U87 and GSC-U251 cells. e Flow cytometry analysis to evaluate the effect of miR-122 and SOX3 on cell apoptosis of GSC-U87 and GSC-U251 cells. f Transwell assay to evaluate the effect of miR-122 and SOX3 on the cell migration and invasion of GSC-U87 and GSC-U251 cells. Data are presented as the mean ± SD (n = 5, each group). Scale bars represent 40 μm. ** P < 0.01 vs. AgomiR-122-NC + SOX3(+)NC group, ## P < 0.01 vs. AgomiR-122 + SOX3(+)NC group
Fig. 7
Fig. 7
TDGF-1 endogenous expression and effect on proliferation, migration, invasion and apoptosis of GSCs. a TDGF-1 protein expression levels in normal brain tissues (NBTs), low-grade glioma tissues (WHO I-II) and high-grade glioma tissues (WHO III-IV) are shown. Data are presented as the mean ± SD (n = 3, each group). b The expression of TDGF-1 in human astrocytes (HA) and glioblastoma cell lines (U87 and U251). c The expression of TDGF-1 in glioblastoma cell lines (U87 and U251) and glioblastoma stem cells (GSC-U87, GSC-U251). d CCK-8 assay was used to measure the effect of TDGF-1 on the proliferation of GSC-U87 and GSC-U251 cells. e The apoptotic percentages of GSC-U87 and GSC-U251 were detected after TDGF-1 over-expression or knockdown. f Transwell assays were used to measure the effect of TDGF-1 on cell migration and invasion of GSC-U87 and GSC-U251 cells. Data are presented as the mean ± SD (n = 5, each group). ** P < 0.01 vs. TDGF-1(+)NC, ## P < 0.01 vs. TDGF-1(−)NC. g Western blot assay of the p-JAK-1/JAK-1 and p-STAT3/STAT3 expression regulated by TDGF-1. Data are presented as the mean ± SD (n = 5, each group). ** P < 0.01 vs. TDGF-1(+)NC, ## P < 0.01 vs. TDGF-1(−)NC. h Weatern blot assay were used to detect the TDGF-1 expression regulated by miR-194-5p and SOX3. Data are presented as the mean ± SD (n = 5, each group). ** P < 0.01 vs. AgomiR-194-5p-NC + SOX3(+)NC group, ## P < 0.01 vs. AgomiR-194-5p + SOX3(+)NC group. i Weatern blot assay were used to detect the TDGF-1 expression regulated by miR-122 and SOX3. Data are presented as the mean ± SD (n = 5, each group). ** P < 0.01 vs. AgomiR-122-NC + SOX3(+)NC group, ## P < 0.01 vs. AgomiR-122 + SOX3(+)NC group
See this image and copyright information in PMC

Erratum for

References

    1. Su R, Cao S, Ma J, et al. Knockdown of SOX2OT inhibits the malignant biological behaviors of glioblastoma stem cells via up-regulating the expression of miR-194-5p and miR-122. Mol Cancer. 2017;16:171. doi: 10.1186/s12943-017-0737-1. - DOI - PMC - PubMed

Publication types

LinkOut - more resources