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. 2022 Dec;85(6):702-769.
doi: 10.1016/j.jinf.2022.10.017. Epub 2022 Oct 20.

The changing epidemiology of PIMS-TS across COVID-19 waves: prospective national surveillance, January 2021 to July 2022, England

Joseph Shingleton  1 , Hannah Williams  1 , Godwin Oligbu  2 , Annabel Powell  2 , Jonathan Cohen  3 , Moshe Arditi  4 , Tiffany Watson-Koszel  5 , Simon Kenny  6 , Nick Gent  1 , Shamez N Ladhani  7
Affiliations

The changing epidemiology of PIMS-TS across COVID-19 waves: prospective national surveillance, January 2021 to July 2022, England

Joseph Shingleton et al. J Infect. 2022 Dec.
No abstract available

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Figures

Fig 1:
Fig. 1
(a) Forecasted PIMS-TS admissions based on a model fitted to the Alpha variant wave of COVID-19, alongside observed PIMS-TS admissions. (b) SARS-CoV-2 variant prevalence using available sequenced strains for England from 1 February 2021 as of 20 June 2022. (c) Mean age of children with by week since December 2020. A Lowess filter with window size 1/3rd was fitted to identify the general trend in the data. Confidence intervals were produced by applying the filter 1000 times to a random subset of 50% of the data.
See this image and copyright information in PMC

References

    1. Flood J., Shingleton J., Bennett E., Walker B. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): prospective, national surveillance, United Kingdom and Ireland. Lancet Reg Health Eur. 2020;3:75–86. 2021. - PMC - PubMed
    1. Shingleton J., Williams H., Burton L. Risk of Paediatric Multisystem Inflammatory Syndrome (PIMS-TS) during the SARS-CoV-2 Alpha and Delta variant waves: national observational study, 2020-21, England,”. SSRN. 2022 - PMC - PubMed
    1. Moshin M., Mahmud S. Omicron SARS-CoV-2 variant of concern: a review on its transmissibility, immune evasion, reinfection, and severity. Medicine (Baltimore) 2022;101 e29165. - PMC - PubMed
    1. Cohen J.M., J C.M., Cheung R.C. Lower risk of Multisystem Inflamatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2. Clin Infect Dis. 2022 - PMC - PubMed
    1. UK Health Security Agency, “SARS-CoV-2 variants of concern and variant under investigation in England,” UK Government, 2022.

Supplementary concepts