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Comment
. 2023 Feb;86(2):e33-e35.
doi: 10.1016/j.jinf.2022.10.026. Epub 2022 Oct 21.

Humoral and cellular responses to the third COVID-19 BNT162b2 vaccine dose in research institute workers in Japan

Akihiko Nishikimi  1 , Takeshi Nakagawa  2 , Mitsuhiro Fujiwara  3 , Ken Watanabe  4 , Atsushi Watanabe  5 , Ayane Komatsu  2 , Mikako Yasuoka  6 , Ryota Watanabe  6 , Masahiro Naya  7 , Hironori Oshima  7 , Yuichi Kitagawa  8 , Haruhiko Tokuda  9 , Izumi Kondo  10 , Shumpei Niida  11 , Takashi Sakurai  11 , Masayo Kojima  6 , Hidenori Arai  12
Affiliations
Comment

Humoral and cellular responses to the third COVID-19 BNT162b2 vaccine dose in research institute workers in Japan

Akihiko Nishikimi et al. J Infect. 2023 Feb.
No abstract available

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Conflict of interest statement

Declarations of Competing Interest The authors declare no competing interests.

Figures

Fig 1
Fig. 1
Humoral and cellular response before and after the third BNT162b2 vaccination dose. (A) Levels of S-IgG in serum on day 0 (n = 86), day 15 (n = 84), day 29 (n = 85), day 61 (n = 83), and day 130–164 (n = 78) after inoculation. (B) Levels of IFN-γ released in response to Ag-1 and Ag-2. Dotted lines indicate the positivity cutoff values. Data are expressed as box plots: middle line, median; box edges, 25th–75th percentile. Statistical comparisons were performed by nonparametric ANOVA, Kruskal–Wallis test.
Fig 2
Fig. 2
Correlation between S-IgG titer and T cell responses before and after the third dose. Correlation between S-IgG levels and IFN-γ levels induced by Ag-1 and Ag-2, respectively, at each point were analyzed by Spearman's rank correlation test. Spearman r and p-values are presented in each graph.
See this image and copyright information in PMC

Comment on

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