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Review
. 2022 Oct;12(10):277.
doi: 10.1007/s13205-022-03321-0. Epub 2022 Sep 13.

Exploring the potential of endophytes and their metabolites for bio-control activity

Ayushi Sharma  1   2 , Nutan Kaushik  1 , Abhishek Sharma  1 , Takwa Marzouk  3 , Naceur Djébali  3
Affiliations
Review

Exploring the potential of endophytes and their metabolites for bio-control activity

Ayushi Sharma et al. 3 Biotech. 2022 Oct.

Abstract

In the current scenario, extensive use of synthetic chemicals in agriculture is creating notable problems such as disease and pest resistance, residues, yield loss, and soil unproductiveness. These harmful chemicals are eventually reaching our food plate through bioaccumulation and biomagnification in a crop. As a result, beneficial microorganisms are regularly being explored as a safer option in the agriculture sector for their ability to produce valuable bioactive secondary metabolites, particularly for crop protection. Such natural (bio) products are harmless to plants, humans, and the environment. In our quest for the search of the sources of bioactive constituents from the microorganisms, endophytes are the front-runner. They mutually reside inside the plant providing support against phytopathogens by releasing an array of bioactive secondary metabolites building climate reliance of the host plant. The purpose of this review is to examine the biocontrol potential of endophytes against bacterial and fungal pathogens in sustainable agriculture. We also attempt to explain the structure and activity of the secondary metabolites produced by bacterial and fungal endophytes in conjunction with their biocontrol function. Additionally, we address potential future research directions for endophytes as biopesticides.

Keywords: Biological control; Endophytes; Phytopathogens; Secondary metabolites; Synthetic pesticides.

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Conflict of interest statement

Conflict of interestThe authors declare that there is no conflict of interest regarding the publication of this manuscript.Informed consentWe affirm that all the authors have seen, prepared, and agreed to the submission of the paper and their inclusion of name(s) as co-author(s). We also declare that there are no conflicts of interest for the same.

Figures

Fig. 1
Fig. 1
Bioactivity mechanisms opted by endophytes to protect plants from biotic stress
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
Fig. 2
Fig. 2
Structures of important and biologically active compounds isolated from various endophytes
See this image and copyright information in PMC

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