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Review
. 2020 Dec 17;14(2):76-79.
doi: 10.17925/HI.2020.14.2.76. eCollection 2020.

Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis

Joshua Beverly  1 , Matthew J Budoff  1
Affiliations
Review

Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis

Joshua Beverly et al. Heart Int. .

Abstract

Coronary artery calcium (CAC) scoring serves as a highly specific marker of coronary atherosclerosis. Based on the results of multiple large-scale, longitudinal population-based studies, CAC scoring has emerged as a reliable predictor of atherosclerotic cardiovascular disease (ASCVD) presence and risk assessment in asymptomatic patients across all age, sex and racial groups. Therefore, the measurement of CAC is useful in guiding clinical decision-making for primary prevention (e.g. use of statin and aspirin). This tool has already been incorporated into the clinical guidelines and is steadily being integrated into standard clinical practice. The adoption of CAC scoring will be important for curbing the progressive burden that ASCVD is exerting on our healthcare system. It has already been projected that CAC testing will decrease healthcare spending and will hopefully be shown to improve ASCVD outcomes. The purpose of this review is to summarise the evidence regarding calcium screening for atherosclerosis, particularly in asymptomatic individuals, including the pathophysiology, the prognostic power of CAC in the context of population-based studies, the progressive inclusion of CAC into clinical guidelines and the existing concerns of cost and radiation.

Keywords: Coronary artery calcium; atherosclerosis; atherosclerotic cardiovascular disease; cardiovascular disease; computed tomography scan; primary prevention; statins.

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Conflict of interest statement

Disclosures: Joshua Beverly and Matthew J Budoff have no financial or non-financial relationships or activities to declare in relation to this article.

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