doi: 10.1007/BF01808239.
The triose model: glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions
Collaborators,
Affiliations
- PMID: 3627761
- DOI: 10.1007/BF01808239
Item in Clipboard
The triose model: glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions
Orig Life Evol Biosph.
1987.
Abstract
Glyceraldehyde acts as a source of energy and monomers in a new model of the origin of life. The simplest form of the model functions by converting formaldehyde from the environment into glyceraldehyde which spontaneously forms hemiacetal adducts that are oxidized to polyglyceric acid. Polyglyceric acid, in turn, acts as an autocatalyst with a rudimentary replicating ability. A unique property of the model is its ability to unite the origin of metabolism and the origin of polymer synthesis into a single process. Furthermore, the chemical resemblance of the model to glycolysis gives it the potential to develop a biological metabolism in a straightforward manner.
Similar articles
-
The first living systems: a bioenergetic perspective.Microbiol Mol Biol Rev. 1997 Jun;61(2):239-61. doi: 10.1128/mmbr.61.2.239-261.1997. Microbiol Mol Biol Rev. 1997. PMID: 9184012 Free PMC article. Review.
-
Prebiotic sugar synthesis: hexose and hydroxy acid synthesis from glyceraldehyde catalyzed by iron(III) hydroxide oxide.J Mol Evol. 1992 Jul;35(1):1-6. doi: 10.1007/BF00160255. J Mol Evol. 1992. PMID: 11536502
-
Thermal synthesis and hydrolysis of polyglyceric acid.Orig Life Evol Biosph. 1989;19(1):7-19. doi: 10.1007/BF01808284. Orig Life Evol Biosph. 1989. PMID: 11536612
-
Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate.Orig Life Evol Biosph. 1989;19:179-86. doi: 10.1007/BF01808151. Orig Life Evol Biosph. 1989. PMID: 11538679
-
Thermal synthesis of amino acids and the origin of life.Geochim Cosmochim Acta. 1995 Mar;59(6):1213-4. doi: 10.1016/0016-7037(95)00037-z. Geochim Cosmochim Acta. 1995. PMID: 11540049 Review.
Cited by
-
The first living systems: a bioenergetic perspective.Microbiol Mol Biol Rev. 1997 Jun;61(2):239-61. doi: 10.1128/mmbr.61.2.239-261.1997. Microbiol Mol Biol Rev. 1997. PMID: 9184012 Free PMC article. Review.
-
On the free energy that drove primordial anabolism.Int J Mol Sci. 2009 Apr 22;10(4):1853-1871. doi: 10.3390/ijms10041853. Int J Mol Sci. 2009. PMID: 19468343 Free PMC article. Review.
-
Prebiotic sugar synthesis: hexose and hydroxy acid synthesis from glyceraldehyde catalyzed by iron(III) hydroxide oxide.J Mol Evol. 1992 Jul;35(1):1-6. doi: 10.1007/BF00160255. J Mol Evol. 1992. PMID: 11536502
-
Energy-rich glyceric acid oxygen esters: implications for the origin of glycolysis.Orig Life Evol Biosph. 1990;20(2):145-50. doi: 10.1007/BF01808275. Orig Life Evol Biosph. 1990. PMID: 2216409
-
Chiral encoding may provide a simple solution to the origin of life.Nat Chem. 2014 Jul;6(7):569-74. doi: 10.1038/nchem.1981. Nat Chem. 2014. PMID: 24950314