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. 2023 Aug 31;142(9):786-793.
doi: 10.1182/blood.2021014818.

How I manage inpatient consultations for quantitative neutrophil abnormalities in adults

Rebecca L Zon  1 , Nancy Berliner  2
Affiliations

How I manage inpatient consultations for quantitative neutrophil abnormalities in adults

Rebecca L Zon et al. Blood. .

Abstract

Neutrophilia and neutropenia commonly lead to inpatient hematology consultation. Quantitative neutrophil abnormalities have a broad differential and include diagnoses that are important to recognize because they may be associated with increased mortality. Neutrophilia can reflect etiologies such as infection, medications, inflammation, splenectomy, and congenital disorders. Neutropenia can arise from infection, medications, autoimmune destruction, sequestration, nutritional deficiency, malignancy, and congenital neutropenia syndromes. In the evaluation of all abnormalities of neutrophil number, the timing of the change, and the patient's historical neutrophil count are crucial.

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Conflict of interest statement

Conflict-of-interest disclosure: R.L.Z. is a consultant and stockholder for Amagma Therapeutics. N.B. declares no competing financial interests.

Figures

None
Graphical abstract
Figure 1.
Figure 1.
Differential of neutrophilia with inpatient consultative questions highlighted in pink.
Figure 2.
Figure 2.
Differential of neutropenia with inpatient consultative questions highlighted in pink.
See this image and copyright information in PMC

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