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. 2022 Nov 1;106(11):2111-2117.
doi: 10.1097/TP.0000000000004186. Epub 2022 Oct 21.

The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation

Beatriz Domínguez-Gil  1 , Nancy L Ascher  2 , Riadh A S Fadhil  3 , Elmi Muller  4 , Marcelo Cantarovich  5 , Curie Ahn  6 , Marina Berenguer  7 , Mirela Bušić  8 , Hiroto Egawa  9 , Gabriel E Gondolesi  10 , Mehmet Haberal  11 , David Harris  12 , Ryutaro Hirose  13 , André Ilbawi  14 , Vivekanand Jha  15 , Marta López-Fraga  16 , Sergio Andrés Madera  17 , Katayoun Najafizadeh  18 , Philip J O'Connell  19 , Axel Rahmel  20 , Faissal A M Shaheen  21 , Ahmed Twahir  22 , Kristof Van Assche  23 , Haibo Wang  24 , Boerje Haraldsson  25 , Efstratios Chatzixiros  26 , Francis L Delmonico  27
Affiliations

The Reality of Inadequate Patient Care and the Need for a Global Action Framework in Organ Donation and Transplantation

Beatriz Domínguez-Gil et al. Transplantation. .

Abstract

Background: Transplant therapy is considered the best and often the only available treatment for thousands of patients with organ failure that results from communicable and noncommunicable diseases. The number of annual organ transplants is insufficient for the worldwide need.

Methods: We elaborate the proceedings of the workshop entitled "The Role of Science in the Development of International Standards of Organ Donation and Transplantation," organized by the Pontifical Academy of Sciences and cosponsored by the World Health Organization in June 2021.

Results: We detail the urgency and importance of achieving national self-sufficiency in organ transplantation as a public health priority and an important contributor to reaching relevant targets of the United Nations Agenda for Sustainable Development. It details the elements of a global action framework intended for countries at every level of economic development to facilitate either the establishment or enhancement of transplant activity. It sets forth a proposed plan, by addressing the technical considerations for developing and optimizing organ transplantation from both deceased and living organ donors and the regulatory oversight of practices.

Conclusions: This document can be used in governmental and policy circles as a call to action and as a checklist for actions needed to enable organ transplantation as treatment for organ failure.

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Conflict of interest statement

The authors declare no funding or conflicts of interest.

References

    1. Global Observatory on Donation and Transplantation. WHO-ONT . Available at http://www.transplant-observatory.org/ . Accessed January 2022.
    1. Aubert O, Yoo D, Zielinski D, et al. COVID-19 pandemic and worldwide organ transplantation: a population-based study. Lancet Public Health. 2021;6:e709–e719.
    1. Sixty-third World Health Assembly Resolution. Human organ and tissue transplantation. Available at https://apps.who.int/gb/ebwha/pdf_files/WHA63/A63_R22-en.pdf . Accessed January 2022.
    1. Luyckx VA, Al-Aly Z, Bello AK, et al. Sustainable development goals relevant to kidney health: an update on progress. Nat Rev Nephrol. 2021;17:15–32.
    1. The Pontifical Academy of Sciences. The role of science in the development of international standards of organ donation and transplantation. Available at https://www.pas.va/en/events/2021/organ_donation.html . Accessed January 2022.