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Comment
. 2022 Oct;610(7933):638-640.
doi: 10.1038/d41586-022-03368-2.

How regulatory T cells are primed to aid tolerance of gut bacteria

Comment

How regulatory T cells are primed to aid tolerance of gut bacteria

Mark A Travis et al. Nature. 2022 Oct.
No abstract available

Keywords: Immunology; Microbiology.

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Comment on

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  • ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.
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References

    1. Caruso, R., Lo, B. C. & Núñez, G. Nature Rev. Immunol. 20, 411–426 (2020). - PubMed - DOI
    1. Lyu, M. et al. Nature 610, 744–751 (2022). - DOI
    1. Kedmi, R. et al. Nature 610, 737–743 (2022). - DOI
    1. Akagbosu, B. et al. Nature 610, 752–760 (2022). - DOI
    1. Sakaguchi, S. et al. Annu. Rev. Immunol. 38, 541–566 (2020). - PubMed - DOI

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