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. 2022 Oct 24;32(20):R1033-R1035.
doi: 10.1016/j.cub.2022.09.025.

Mechanosensation: Capping actin filaments for robustness

Alex Mogilner  1 , Christopher E Miles  2
Affiliations
Free article

Mechanosensation: Capping actin filaments for robustness

Alex Mogilner et al. Curr Biol. .
Free article

Abstract

Actin networks adapt to resistance by becoming denser. A recent investigation shows that this mechanosensation relies on a force-sensitive mechanical ratchet of capping actin filaments to reorganize the network. This and other mechanical feedback mechanisms make actin-based protrusion amazingly robust.

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Conflict of interest statement

Declaration of interests A.M. is a member of the journal’s advisory board.

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