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Case Reports
. 2022 Oct 25;15(10):e252287.
doi: 10.1136/bcr-2022-252287.

Malignant acanthosis nigricans: a cutaneous marker of hepatocellular carcinoma

Affiliations
Case Reports

Malignant acanthosis nigricans: a cutaneous marker of hepatocellular carcinoma

Konsam Nirupama Devi et al. BMJ Case Rep. .
No abstract available

Keywords: Dermatology; Gastrointestinal system; Hepatic cancer.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) Ill-defined hyperpigmented velvety plaque present over the vertex of the scalp. (B) Diffused hyperpigmented velvety plaque present over buttocks and perianal area. (C) Groups of multiple pebble-like rough papules coalescing to form plaques present over the dorsal aspect of knuckles and interphalangeal joints; Huntley’s papules. (D) Prominent rough dermatoglyphic ridging present on the palm; tripe palm.

References

    1. Pentenero M, Carrozzo M, Pagano M, et al. . Oral acanthosis nigricans, tripe palms and sign of Leser-Trélat in a patient with gastric adenocarcinoma. Int J Dermatol 2004;43:530–2. 10.1111/j.1365-4632.2004.02159.x - DOI - PubMed
    1. Kahn CR, Flier JS, Bar RS, et al. . The syndromes of insulin resistance and acanthosis nigricans. insulin-receptor disorders in man. N Engl J Med 1976;294:739–45. 10.1056/NEJM197604012941401 - DOI - PubMed

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