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Case Reports
. 2023 Feb;10(1):716-720.
doi: 10.1002/ehf2.14219. Epub 2022 Oct 25.

Pressures do not equal volumes: implications for heart failure management in patients with CardioMEMS

Muhammad Shahzeb Khan  1 , Michel G Khouri  1 , Leilani Gomez  1 , Marat Fudim  1   2
Affiliations
Case Reports

Pressures do not equal volumes: implications for heart failure management in patients with CardioMEMS

Muhammad Shahzeb Khan et al. ESC Heart Fail. 2023 Feb.

Abstract

Pulmonary arterial pressures are often used as surrogates for intravascular blood volume. However, the relationship between pressure and volume remains controversial. To contextualize and provide concrete examples and impact on clinical management, we report two cases of heart failure (one in heart failure with reduced ejection fraction and one in heart failure with preserved ejection fraction) where pressure-based measurements did not accurately represent the intravascular status and affected clinical management.

Keywords: CardioMEMS; Heart failure; Pressure; Volume.

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Conflict of interest statement

Dr Fudim was supported by the National Heart, Lung, and Blood Institute (NHLBI) (K23HL151744), the American Heart Association (20IPA35310955), Bayer, Bodyport, BTG Specialty Pharmaceuticals, and Verily. He receives consulting fees from Abbott, Alleviant, Audicor, AxonTherapies, Bayer, Bodyguide, Bodyport, Boston Scientific, Coridea, CVRx, Daxor, Deerfield Catalyst, Edwards LifeSciences, Feldschuh Foundation, Fire1, Gradient, Intershunt, Medtronic, NXT Biomedical, Pharmacosmos, PreHealth, Shifamed, Splendo, Vironix, Viscardia, and Zoll.

Figures

Figure 1
Figure 1
Recordings from CardioMEMS for Case 1. The figure shows the implant time, and changes in pulmonary artery pressures after that. PA, pulmonary artery.
Figure 2
Figure 2
Recordings from CardioMEMS for Case 2. The figure shows the implant time, and changes in pulmonary artery pressures after that. PA, pulmonary artery.
See this image and copyright information in PMC

References

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