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Comment
. 2022 Oct;610(7933):620-622.
doi: 10.1038/d41586-022-03392-2.

Cancer drugs are closing in on some of the deadliest mutations

Heidi Ledford
Comment

Cancer drugs are closing in on some of the deadliest mutations

Heidi Ledford. Nature. 2022 Oct.
No abstract available

Keywords: Biotechnology; Cancer; Drug discovery.

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  • Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor.
    Wang X, Allen S, Blake JF, Bowcut V, Briere DM, Calinisan A, Dahlke JR, Fell JB, Fischer JP, Gunn RJ, Hallin J, Laguer J, Lawson JD, Medwid J, Newhouse B, Nguyen P, O'Leary JM, Olson P, Pajk S, Rahbaek L, Rodriguez M, Smith CR, Tang TP, Thomas NC, Vanderpool D, Vigers GP, Christensen JG, Marx MA. Wang X, et al. J Med Chem. 2022 Feb 24;65(4):3123-3133. doi: 10.1021/acs.jmedchem.1c01688. Epub 2021 Dec 10. J Med Chem. 2022. PMID: 34889605

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