Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep 30;4(39):875-878.
doi: 10.46234/ccdcw2022.181.

Strengthening Systematic Research on Aging: Reflections from an Omics Perspective

Xiaoying Zheng  1 , Chao Guo  2
Affiliations

Strengthening Systematic Research on Aging: Reflections from an Omics Perspective

Xiaoying Zheng et al. China CDC Wkly. .

Abstract

Population aging has become a global concern in population development. Challenges to good health in older ages are more complex than at any other age and require a comprehensive framework to move the science of aging and health forward. In this paper, we describe an advanced and evolving conceptual framework that includes definitions, goals, disciplines, and a scope of human aging omics (HAO) based on theories and methods of omics science. The development of HAO will bring a paradigm shift in research related to aging and health by systematic identification, characterization, and quantification of all sets of health conditions and their complex relationships with the internal biomolecules and the external environment in the whole aging process of human beings from birth to death throughout the lifespan.

Keywords: Aging and health; Human aging omics; Omics; Systematic research.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A conceptual framework of human aging omics.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. United Nations, Department of Economic and Social Affairs, Population Division. World population prospects 2022: Ten Key Messages. 2022. https://population.un.org/wpp/. [2022-8-26].

    1. World Health Organization. World health statistics 2022: monitoring health for the SDGs, sustainable development goals. Geneva: World Health Organization; 2022. https://www.who.int/publications-detail-redirect/9789240051157.

    1. Yang WZ, Leng ZW, Shan GL, Wang C Population medicine: a newly emerging subject healing the schism between preventive medicine and clinical medicine. Natl Med J China. 2020;100(26):2001–5. doi: 10.3760/cma.j.cn112137-20200515-01549. - DOI - PubMed

    1. Binder H, Wirth H. Analysis of large-scale OMIC data using self organizing maps. In: Khosrow-Pour M, editor. Encyclopedia of information science and technology. 3rd ed. Hershey: IGI Global. 2015; p. 1642 − 53. https://doi.org/10.4018/978-1-4666-5888-2.ch157.

    1. Solanke AU, Tribhuvan KU, Kanika. Genomics: an integrative approach for molecular biology. In: Khurana SMP, Singh M, editors. Biotechnology—progress and prospects. Delhi: Studium Press. 2015; 234-70. https://www.researchgate.net/publication/283084372_Genomics_An_Integrative_Approach_for_Molecular_Biology.

LinkOut - more resources