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. 2022 Oct 12;94(8):935-939.
doi: 10.26442/00403660.2022.08.201787.

[Prospects for personalized Helicobacter pylori eradication therapy. Pro et contra]

[Article in Russian]
Affiliations

[Prospects for personalized Helicobacter pylori eradication therapy. Pro et contra]

[Article in Russian]
V I Simanenkov et al. Ter Arkh. .

Abstract

The article is devoted to debatable aspects of Helicobacter pylori eradication therapy. The eradication cancer-preventive effects are considered. A negative comorbidity between H. pylori infection and such diseases as gastroesophageal reflux disease, inflammatory bowel disease and bronchial asthma has been described. The perspectives of populational, individualized and personalized strategies for H. pylori eradication therapy assessment are given. Recommendations for individualized H. pylori eradication strategy implementation in practical healthcare are proposed.

Статья посвящена дискуссионным аспектам эрадикационной терапии Helicobacter pylori. Рассмотрены канцеропревентивные эффекты эрадикации. Описана отрицательная коморбидность между хеликобактерной инфекцией и такими патологиями, как гастроэзофагеальная рефлюксная болезнь, воспалительные заболевания кишечника и бронхиальная астма. Дана оценка перспектив применения популяционной, индивидуализированной и персонифицированной стратегий H. pylori-эрадикационной терапии. Предложены рекомендации по реализации индивидуализированной стратегии эрадикации H. pylori в практическом здравоохранении.

Keywords: Helicobacter pylori; bronchial asthma; cancer prevention; gastroesophageal reflux disease; inflammatory bowel disease; personalized eradication.

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