Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Aug;111(2):185-91.

Proliferation activity of stromal stem cells (CFU-f) from hemopoietic organs of pre- and postnatal mice

S R Versele, R L Van den Heuvel, G E Schoeters, O L Vanderborght
  • PMID: 3628711

Proliferation activity of stromal stem cells (CFU-f) from hemopoietic organs of pre- and postnatal mice

S R Versele et al. Radiat Res. 1987 Aug.

Abstract

Stromal stem cells (CFU-f assay) from hemopoietic organs of fetuses, in contrast to adult animals, exhibit a high proliferation activity. This implies that these CFU-f are radiosensitive and potential target cells after radioactive contamination of fetuses. Furthermore, the percentage of CFU-f in DNA synthesis is correlated with the hemopoietic activity in liver, spleen, and bone marrow. As hemopoiesis starts, high numbers of CFU-f are in S phase. In fetal liver, spleen, and bone marrow, values of 70, 43, and 58%, respectively, are reached. As hemopoietic activity decreases in liver and stabilizes in spleen and bone marrow, mitotic activity of these stromal stem cells becomes undetectable.

PubMed Disclaimer

Publication types

LinkOut - more resources