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Editorial
. 2022 Nov;42(11):1351-1354.
doi: 10.1161/ATVBAHA.122.318468. Epub 2022 Oct 26.

How Irritating! Electronic Cigarettes Not "95% Safer" Than Combustible Cigarettes: Recent Mechanistic Insights Into Endothelial Dysfunction

Daniel J Conklin  1
Affiliations
Editorial

How Irritating! Electronic Cigarettes Not "95% Safer" Than Combustible Cigarettes: Recent Mechanistic Insights Into Endothelial Dysfunction

Daniel J Conklin. Arterioscler Thromb Vasc Biol. 2022 Nov.

Erratum in

No abstract available

Keywords: Editorials; acrolein; aldehydes; endothelium; inflammation; irritants; nitric oxide; tobacco.

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Conflict of interest statement

CONFLICTS OF INTEREST

Author declares no conflicts of interest in this paper. The content is solely the responsibility of the author and does not necessarily represent the official views of the National Institutes of Health, the Food and Drug Administration, the U.S. Environmental Protection Agency, or the American Heart Association.

Figures

Scheme:
Scheme:
Novel insights into mechanisms of endothelial dysfunction (impaired flow-mediated dilation, FMD) induced by electronic cigarette aerosol exposure (acute pathway: rats) and chronic use (chronic pathway: human E-cig users) as revealed in the complementary studies in this issue of ATVB (#, pgs). Abbreviations: AA, acetaldehyde, PG:G, propylene glycol:glycerin; RAGE, receptor of advanced glycation endproducts.
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Comment on

References

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    1. American Heart Association. Smoking & cardiovascular disease (heart disease). 2014;2017
    1. U.S. Department of Health and Human Services. The health consequences of smoking—50 years of progress: A report of the surgeon general, 2014. 2014
    1. U.S. Food & Drug Administration. Harmful and potentially harmful constituents in tobacco products and tobacco smoke: Established list. 2012;2017

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