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. 2022 Oct 6;12(10):833.
doi: 10.3390/bios12100833.

A Contact-Free Optical Device for the Detection of Pulmonary Congestion-A Pilot Study

Ilan Merdler  1 , Aviram Hochstadt  1 , Eihab Ghantous  1 , Lior Lupu  1 , Ariel Borohovitz  1 , David Zahler  1 , Philippe Taieb  1 , Ben Sadeh  1 , Zeev Zalevsky  2   3 , Javier Garcia-Monreal  2   4 , Michael Shergei  2 , Maxim Shatsky  2 , Yoav Beck  2 , Sagi Polani  2 , Yaron Arbel  1   2
Affiliations

A Contact-Free Optical Device for the Detection of Pulmonary Congestion-A Pilot Study

Ilan Merdler et al. Biosensors (Basel). .

Abstract

Background: The cost of heart failure hospitalizations in the US alone is over USD 10 billion per year. Over 4 million Americans are hospitalized every year due to heart failure (HF), with a median length of stay of 4 days and an in-hospital mortality rate that exceeds 5%. Hospitalizations of patients with HF can be prevented by early detection of lung congestion. Our study assessed a new contact-free optical medical device used for the early detection of lung congestion.

Methods: The Gili system is an FDA-cleared device used for measuring chest motion vibration data. Lung congestion in the study was assessed clinically and verified via two cardiologists. An algorithm was developed using machine learning techniques, and cross-validation of the findings was performed to estimate the accuracy of the algorithm.

Results: A total of 227 patients were recruited (101 cases vs. 126 controls). The sensitivity and specificity for the device in our study were 0.91 (95% CI: 0.86-0.93) and 0.91 (95% CI: 0.87-0.94), respectively. In all instances, the observed estimates of PPVs and NPVs were at least 0.82 and 0.90, respectively. The accuracy of the algorithm was not affected by different covariates (including respiratory or valvular conditions).

Conclusions: This study demonstrates the efficacy of a contact-free optical device for detecting lung congestion. Further validation of the study results across a larger and precise scale is warranted.

Keywords: camera; congestion; contact-free; heart failure; increased lung fluid content; remote monitoring.

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Conflict of interest statement

Z.Z., J.G.M., M.S. (Michael Shergeiand), M.S. (Maxim Shatsky), Y.B., S.P. and Y.A. hold equity with Donisi Health.

Figures

Figure 1
Figure 1
The “Gili” device and measurement setup.
Figure 2
Figure 2
Schematic sketch of the developed algorithm.
Figure 3
Figure 3
Study flowchart.
Figure 4
Figure 4
Representative spectrograms of signals.
Figure 5
Figure 5
Receiver–operator characteristics. Numbers in brackets represent 95% confidence intervals (CI). Black dot marks the chosen threshold on the curve for the reported.
Figure 6
Figure 6
Effect of measurement duration on the algorithm’s performance.
Figure 7
Figure 7
A contact-free optical device for the detection of pulmonary congestion.
See this image and copyright information in PMC

References

    1. Cook C., Cole G., Asaria P., Jabbour R., Francis D.P. The annual global economic burden of heart failure. Int. J. Cardiol. 2014;171:368–376. doi: 10.1016/j.ijcard.2013.12.028. - DOI - PubMed
    1. Jackson S.L., Tong X., King R.J., Loustalot F., Hong Y., Ritchey M.D. National Burden of Heart Failure Events in the United States, 2006 to 2014. Circ. Heart Fail. 2018;11:e004873. doi: 10.1161/CIRCHEARTFAILURE.117.004873. - DOI - PMC - PubMed
    1. van Riet E.E.S., Hoes A.W., Wagenaar K.P., Limburg A., Landman M.A.J., Rutten F.H. Epidemiology of heart failure: The prevalence of heart failure and ventricular dysfunction in older adults over time. A systematic review. Eur. J. Heart Fail. 2016;18:242–252. doi: 10.1002/ejhf.483. - DOI - PubMed
    1. Fida N., Piña I.L. Trends in heart failure hospitalizations. Curr. Heart Fail. Rep. 2012;9:346–353. doi: 10.1007/s11897-012-0117-5. - DOI - PubMed
    1. Alghamdi F., Chan M. Management of heart failure in the elderly. Curr. Opin. Cardiol. 2017;32:217–223. doi: 10.1097/HCO.0000000000000375. - DOI - PubMed