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. 2022 Oct 15;12(10):1393.
doi: 10.3390/brainsci12101393.

The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study

Ying Lu  1 , Yu Tian  1 , Yu Gan  2 , Yixiao Fu  3 , Qibin Chen  4 , Lei Zou  4 , Bangshu Zhao  4 , Yu Yan  5 , Shudong Liu  6 , Xiaolu Chen  7 , Xiao Li  3
Affiliations

The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study

Ying Lu et al. Brain Sci. .

Abstract

Electroconvulsive therapy (ECT) is an effective therapy for many psychiatric illnesses. However, intracranial occupying lesions are a relative contraindication to ECT. Arachnoid cysts are benign, congenital, and space-occupying lesions. Our study aimed to evaluate the efficacy and tolerability of ECT in psychiatric patients with arachnoid cysts. We retrospectively identified 62 psychiatric patients with arachnoid cysts; 43 of them underwent ECT and 19 did not. Their conditions were assessed by CGI-S and different scales depending on different diagnoses (PANSS for schizophrenia; HAMD for depression; YMRS for bipolar disorder). The side effect was assessed by TESS. Significant differences were shown in the reduced scores of the CGI-S between patients who underwent ECT and those who did not (p = 0.001), while, at the same time, there was no significant difference in their TESS score (p = 0.297). The current study found that ECT is an effective and tolerable therapy for psychiatric patients with arachnoid cysts.

Keywords: ECT; arachnoid cysts; bipolar disorder; depression; psychiatry; retrospective study; schizophrenia.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
This is a figure that shows the location of brain regions or hemisphere where the cysts were located in patients with different diagnoses.
See this image and copyright information in PMC

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