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Review
. 2022 Oct 12;11(20):6017.
doi: 10.3390/jcm11206017.

How to Recognize and Treat Small Intestinal Bacterial Overgrowth?

Barbara Skrzydło-Radomańska  1 , Bożena Cukrowska  2
Affiliations
Review

How to Recognize and Treat Small Intestinal Bacterial Overgrowth?

Barbara Skrzydło-Radomańska et al. J Clin Med. .

Abstract

Small Intestinal Bacterial Overgrowth (SIBO) is a form of dysbiosis that involves increased bacterial colonization of the small intestine with some of the bacteria more characteristic of the colon microbiota. The prevalence of SIBO over recent decades has been estimated to range from 2.5 to 22% (depending on the source) and to increase with age and among individuals with comorbidities. Recently, an increase in the number of diagnosed SIBO cases has been observed, which is primarily due to the availability of noninvasive breath tests that facilitate the diagnostic process. However, SIBO is still both a diagnostic and a therapeutic problem. This review presents the pathophysiology, manifestations, diagnostics, and recommended management of SIBO.

Keywords: SIBO; dysbiosis; microbiota; probiotics; rifaximin.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Clinical presentation of SIBO.
See this image and copyright information in PMC

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