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Review
. 2022 Sep 29;10(10):1637.
doi: 10.3390/vaccines10101637.

COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis

Petros Galanis  1 , Irene Vraka  2 , Aglaia Katsiroumpa  1 , Olga Siskou  3 , Olympia Konstantakopoulou  4 , Theodoros Katsoulas  5 , Theodoros Mariolis-Sapsakos  5 , Daphne Kaitelidou  4
Affiliations
Review

COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis

Petros Galanis et al. Vaccines (Basel). .

Abstract

The vaccine-induced immunity of healthcare workers (HCWs) is crucial to controlling the COVID-19 pandemic. Therefore, we conducted a systematic review and meta-analysis to assess the COVID-19 vaccine uptake among HCWs worldwide and to identify predictors of vaccination. We searched Scopus, Web of Science, Medline, PubMed, ProQuest, CINAHL, and medRxiv up to 25 August 2022. We applied the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We found 25 studies including 491,624 vaccinated HCWs, while the full sample included 555,561 HCWs. The overall proportion of vaccinated HCWs was 77.3%. Vaccine uptake for studies that were conducted in North America (85.6%) was higher than the proportion for studies that were conducted in Asia (79.5%), Europe (72.8%), and Africa (65.6%). The overall prevalence of COVID-19 vaccine uptake was 83.6% and 77.4% for physicians and nurses, respectively. Older age, white race, physicians' profession, seasonal influenza vaccine, direct COVID-19 patient care, and confidence in COVID-19 vaccine safety and effectiveness were positive predictors of vaccine uptake, while history of SARS-CoV-2 infection was a negative predictor. Deep understanding of the factors that influence HCWs' decisions to receive a COVID-19 vaccine is critical to implementing tailored communication strategies for HCWs who are at risk for not getting vaccinated.

Keywords: COVID-19; healthcare workers; predictors; vaccination.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of the literature search according to the PRISMA guidelines.
Figure 2
Figure 2
Forest plot of healthcare workers vaccinated against COVID-19 [32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56].
Figure 3
Figure 3
Forest plot of physicians vaccinated against COVID-19 [34,35,37,38,40,41,43,44,45,46,48,49,52,53,55].
Figure 4
Figure 4
Forest plot of nurses vaccinated against COVID-19 [32,34,37,43,44,45,48,49,52,53,55].
See this image and copyright information in PMC

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