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Review
. 2022 Sep 29;10(10):1639.
doi: 10.3390/vaccines10101639.

An Update on Complications Associated with SARS-CoV-2 Infection and COVID-19 Vaccination

Purvita Chowdhury  1 , Shinjini Bhattacharya  1 , Bhaskarjyoti Gogoi  2 , Ravindra P Veeranna  3 , Sachin Kumar  1
Affiliations
Review

An Update on Complications Associated with SARS-CoV-2 Infection and COVID-19 Vaccination

Purvita Chowdhury et al. Vaccines (Basel). .

Abstract

Over the past two years, SARS-CoV-2 has dramatically spread worldwide and emerged as a major pandemic which has left an unprecedented mark on healthcare systems and economies worldwide. As our understanding of the virus and its epidemiology continues to grow, the acute phase clinical symptoms and long-term and vaccine-related complications are becoming more apparent. With heterogeneity in presentations, comparisons may be drawn between COVID-19-related sequelae and vaccination related adverse events. The present review article aims to address the currently available literature on the SARS-CoV-2 virus, immune responses, the pathophysiology of clinical presentations, and available vaccinations with its adverse events for the appraisal of its potential impact on the COVID-19 management system.

Keywords: COVID; coronavirus; immunity; pathogenesis; vaccines.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic representation of complications in different organ system during acute and long-term sequelae of COVID-19 as well as adverse events post COVID-19 vaccination.
See this image and copyright information in PMC

References

    1. Coronaviridae Study Group of the International Committee on Taxonomy of Viruses The species Severe acute respiratory syndrome-related coronavirus: Classifying 2019-nCoV and naming it SARS-CoV-2. Nat. Microbiol. 2020;5:536–544. doi: 10.1038/s41564-020-0695-z. - DOI - PMC - PubMed
    1. Dhama K., Patel S.K., Pathak M., Yatoo M.I., Tiwari R., Malik Y.S., Singh R., Sah R., Rabaan A.A., Bonilla-Aldana D.K., et al. An update on SARS-CoV-2/COVID-19 with particular reference to its clinical pathology, pathogenesis, immunopathology and mitigation strategies. Travel Med. Infect. Dis. 2020;37:101755. doi: 10.1016/j.tmaid.2020.101755. - DOI - PMC - PubMed
    1. Cucinotta D., Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020;91:157–160. doi: 10.23750/abm.v91i1.9397. - DOI - PMC - PubMed
    1. Viana R., Moyo S., Amoako D.G., Tegally H., Scheepers C., Althaus C.L., Anyaneji U.J., Bester P.A., Boni M.F., Chand M.J.N. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature. 2022;603:679–686. doi: 10.1038/s41586-022-04411-y. - DOI - PMC - PubMed
    1. COVID-19 Vaccine Tracker and Landscape. 2022. [(accessed on 30 June 2022)]. Available online: https://www.who.int/publications/m/item/draft-landscape-of-covid-19-cand....