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. 2022 Oct 24;8(4):00186-2022.
doi: 10.1183/23120541.00186-2022. eCollection 2022 Oct.

Investigation of the frequency of obstructive sleep apnoea syndrome in patients with subclinical hypothyroidism

Affiliations

Investigation of the frequency of obstructive sleep apnoea syndrome in patients with subclinical hypothyroidism

Aysegul Gencer et al. ERJ Open Res. .

Abstract

Background: The aim of this study is to determine the frequency of obstructive sleep apnoea syndrome (OSAS) in a study group with the diagnosis of subclinical hypothyroidism and in a control group without the diagnosis of subclinical hypothyroidism. This study compares these two groups in terms of demographic characteristics, chronic diseases and especially polysomnographic data.

Methods: A total of 120 patients were included in this study. They consisted of 60 patients with newly diagnosed subclinical hypothyroidism and a control group of 60 patients with normal thyroid functions. Demographic, anthropometric, polysomnography data and Epworth Sleepiness Scale scores of the patients were recorded and compared.

Results: Any significant difference in the frequency and severity of OSAS was not detected. A significant difference was found in the oxygen desaturation index (ODI), the apnoea-hypopnoea index (AHI) in rapid eye movement sleep, the AHI in supine sleep position and the arousal index of the group experiencing subclinical hypothyroidism with OSAS.

Conclusion: This study showed that there was no increase in OSAS frequency in patients with subclinical hypothyroidism, but it demonstrated that the ODI and the arousal index were significantly increased in OSAS patients diagnosed with subclinical hypothyroidism. It is thought that the diagnosis and treatment of OSAS in these patients may be important in preventing cardiovascular complications.

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Conflict of interest statement

Conflict of interests: A. Gencer has nothing to disclose. Conflict of interest: E. Atahan has nothing to disclose. Conflict of interest: P. Kadioglu has nothing to disclose. Conflict of interest: B. Mutlu has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Distribution of oxygen desaturation index values in the patient and the control groups.

References

    1. Tondo P, Fanfulla F, Sabato R, et al. Obstructive sleep apnoea-hypopnoea syndrome (OSAHS): state of the art. Minerva Med 2022; in press [ 10.23736/S0026-4806.22.08190-3]. - DOI - PubMed
    1. McNicholas W, Bonsignore M, Management Committee of EU COST ACTION B26. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 2007; 29: 156–178. doi: 10.1183/09031936.00027406 - DOI - PubMed
    1. Kokturk, O. The epidemiology of obstructive sleep apnea syndrome. J Tuberc Thorax J 1998; 46: 193–201.
    1. Schwartz M, Acosta L, Hung Y-L, et al. Effects of CPAP and mandibular advancement device treatment in obstructive sleep apnea patients: a systematic review and meta-analysis. Sleep Breath 2018; 22: 555–568. doi: 10.1007/s11325-017-1590-6 - DOI - PubMed
    1. Khokhrina A, Andreeva E, Degryse J-M. The prevalence of sleep-disordered breathing in northwest Russia: the ARKHsleep study. Chron Respir Dis 2020; 17: 147997312092810. doi: 10.1177/1479973120928103 - DOI - PMC - PubMed

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