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. 2022 Oct 26;93(5):e2022211.
doi: 10.23750/abm.v93i5.12633.

Rhinosinusitis: clinical-based phenotyping

Giorgio Ciprandi  1 , Desiderio Passali  2 , Luisa Maria Bellussi  3 , Francesco Maria Passali  4
Affiliations

Rhinosinusitis: clinical-based phenotyping

Giorgio Ciprandi et al. Acta Biomed. .

Abstract

Rhinosinusitis (RS) is a common disease and is currently classified into two main types: acute RS (ARS) and chronic RS (CRS), which in turn includes CRS with or without nasal polyps. Different guidelines consider this classification. However, in clinical practice, other phenotypes exist. The current article would propose new clinical-based phenotyping of RS, including the following clinical phenotypes: simple catarrhal RS, Acute RS, acute bacterial RS, severe (complicated) acute RS, chronic RS, and recurrent chronic RS. Treatment strategy should be tailored considering the clinical phenotype and could include phytomedicines, intranasal non-pharmacological remedies, and local bacteriotherapy. In conclusion, RS requires thorough diagnostic work-up, and the therapeutic approach should be mainly based on appropriate management.

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Conflict of interest statement

Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article

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