Tuning neurodegeneration-linked gene expression, one (edited) base at a time

Affiliations

¹ Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, United States.
² Department of Bioengineering, Rice University, Houston, TX, United States.
³ Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, United States; Department of Bioengineering, Rice University, Houston, TX, United States. Electronic address: isaac.hilton@rice.edu.

Comment

Rosa Selenia Guerra-Resendez et al. Mol Ther. 2022.

. 2022 Dec 7;30(12):3512-3514.

doi: 10.1016/j.ymthe.2022.10.003. Epub 2022 Oct 27.

¹ Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, United States.
² Department of Bioengineering, Rice University, Houston, TX, United States.
³ Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, United States; Department of Bioengineering, Rice University, Houston, TX, United States. Electronic address: isaac.hilton@rice.edu.

No abstract available

Comment on

CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes.
Lim CKW, McCallister TX, Saporito-Magriña C, McPheron GD, Krishnan R, Zeballos C MA, Powell JE, Clark LV, Perez-Pinera P, Gaj T. Lim CKW, et al. Mol Ther. 2022 Dec 7;30(12):3619-3631. doi: 10.1016/j.ymthe.2022.08.008. Epub 2022 Aug 13. Mol Ther. 2022. PMID: 35965414 Free PMC article.

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