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Case Reports
. 2022 Aug 11;35(6):820-821.
doi: 10.1080/08998280.2022.2108991. eCollection 2022.

Recurrent benign lymphocytic (Mollaret's) meningitis due to herpes simplex virus type 2

Michael Grinney  1 , Michael M Mohseni  1
Affiliations
Case Reports

Recurrent benign lymphocytic (Mollaret's) meningitis due to herpes simplex virus type 2

Michael Grinney et al. Proc (Bayl Univ Med Cent). .

Abstract

We present a rare case of Mollaret's meningitis in a young patient with seven prior episodes of recurrent meningitis. The patient presented with headache, fever, neck stiffness, nausea, and vomiting. Brain imaging revealed no acute abnormalities. Lumbar puncture revealed elevated nucleated cells with lymphocytic predominance. The patient was started on antimicrobials including acyclovir. Cerebrospinal fluid polymerase chain reaction was positive for herpes simplex virus type 2. Her 2-day hospital course was uncomplicated, and she was discharged in good condition. Mollaret's meningitis, also known as recurrent benign lymphocytic meningitis, is a rare clinical disorder characterized by at least three recurrent episodes of meningitis associated with spontaneous recovery with or without antiviral therapy. Herpes simplex virus type 2 has frequently been implicated in the setting of this illness.

Keywords: HSV-2; Mollaret’s meningitis; recurrent benign lymphocytic meningitis; recurrent meningitis.

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References

    1. Adriani KS, van de Beek D, Brouwer MC, Spanjaard L, de Gans J.. Community-acquired recurrent bacterial meningitis in adults. Clin Infect Dis. 2007;45(5):e46–e51. doi:10.1086/520682. - DOI - PubMed
    1. Durand ML, Calderwood SB, Weber DJ, et al. . Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med. 1993;328(1):21–28. doi:10.1056/NEJM199301073280104. - DOI - PubMed
    1. Rosenberg J, Galen BT.. Recurrent meningitis. Curr Pain Headache Rep. 2017;21(7):33. doi:10.1007/s11916-017-0635-7. - DOI - PubMed
    1. Parisi SG, Basso M, Del Vecchio C, et al. . Viral infections of the central nervous system in elderly patients: a retrospective study. Int J Infect Dis. 2016;44:8–10. doi:10.1016/j.ijid.2016.01.012. - DOI - PubMed
    1. Jarrin I, Sellier P, Lopes A, et al. . Etiologies and management of aseptic meningitis in patients admitted to an internal medicine department. Medicine (Baltimore). 2016;95(2):e2372. doi:10.1097/MD.0000000000002372. - DOI - PMC - PubMed

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