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Review
. 2023 Jan 1;34(1):9-20.
doi: 10.1097/ICU.0000000000000912. Epub 2022 Oct 20.

Management of inflammation after the cataract surgery

Andrzej Grzybowski  1   2 , Agne Sidaraite  3 , Reda Zemaitiene  3
Affiliations
Review

Management of inflammation after the cataract surgery

Andrzej Grzybowski et al. Curr Opin Ophthalmol. .

Abstract

Purpose of review: To review most recent studies and clinical trials regarding pathogenesis, treatment, and prevention of inflammation after the cataract surgery.

Recent findings: FLACS gave opportunity to evaluate inflammatory cytokines in the aqueous humour right after the laser procedure, which led to acknowledging the inflammation pathogenesis during the phacoemulsification. Although there is still a lack of evidence, which would prove the long-term benefit of NSAIDs, they are indicated and effective when risk factors for PCME are present. PREMED studies showed that combination of NSAID and steroids after the surgery for healthy subjects is cost-effective. The triamcinolone injection together with topical steroids and NSAIDs for diabetic patients after the cataract surgery was the most cost-effective in preventing PCME according to the PREMED. Dropless cataract surgery is another emerging topic: dexamethasone implants and suspensions look promising as we await more clinical trials with drug-loaded IOLs.

Summary: Inflammation after the cataract surgery can be prevented, and these methods are one of the most essential topics with growing phacoemulsification rate. Topical NSAIDs are cost-effective not only for patients with risk factors for PCME but also for healthy subjects. New dropless techniques are being successfully introduced in the clinical practice.

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References

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    1. American Academy of Ophthalmology Preferred Practice Pattern Cataract and Anterior Segment Committee. Cataract in the adult eye preferred practice pattern 2021. Available at: https://www.aao.org/preferred-practice-pattern/cataract-in-adult-eyeppp . 2021. [in press] [Accessed 10 August 2022].