Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Jan 4;29(1):8-10.
doi: 10.1158/1078-0432.CCR-22-2853.

Brain Metastasis from HER2-Positive Breast Cancer: An Evolving Landscape

Riccardo Soffietti, Alessia Pellerino
Editorial

Brain Metastasis from HER2-Positive Breast Cancer: An Evolving Landscape

Riccardo Soffietti et al. Clin Cancer Res. .

Abstract

Trastuzumab deruxtecan is a HER2-directed antibody-drug conjugate with ability to cross the blood-tumor barrier and activity on brain metastases. To test the activity of new drugs, patient-derived xenograft models from human brain metastases and phase 0 and window-of-opportunity trials are of utmost importance. See related article by Kabraji et al., p. 174.

PubMed Disclaimer

Comment in

Comment on