On the way to translate GWAS into kidney disease mechanisms

Affiliations

¹ Department of Physiology, Mechanisms of Inherited Kidney Disorders, University of Zurich, Zurich, Switzerland. Electronic address: olivier.devuyst@uzh.ch.
² Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.

Comment

Olivier Devuyst et al. Kidney Int. 2023 Jan.

. 2023 Jan;103(1):16-18.

doi: 10.1016/j.kint.2022.10.004. Epub 2022 Oct 26.

¹ Department of Physiology, Mechanisms of Inherited Kidney Disorders, University of Zurich, Zurich, Switzerland. Electronic address: olivier.devuyst@uzh.ch.
² Division of Nephrology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.

No abstract available

Keywords: cell signaling; chronic kidney disease; gene expression; proximal tubule; transcription regulation.

Comment on

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.
Liu H, Doke T, Guo D, Sheng X, Ma Z, Park J, Vy HMT, Nadkarni GN, Abedini A, Miao Z, Palmer M, Voight BF, Li H, Brown CD, Ritchie MD, Shu Y, Susztak K. Liu H, et al. Nat Genet. 2022 Jul;54(7):950-962. doi: 10.1038/s41588-022-01097-w. Epub 2022 Jun 16. Nat Genet. 2022. PMID: 35710981 Free PMC article.